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Egyptian Rheumatology and Rehabilitation
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  1. We aimed to provide a consensus, evidence-based recommendations for the diagnosis, evaluation, and treat-to-target management of children living with FMF.

    Authors: S. Salah, H. Lotfy, M. H. Abu-Zaid, M. El Gaafary, H. Abdulhady, H. Salah, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa, G. El Deriny…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:39
    Content type: Research Published on:

  2. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yasser El Miedany, Naglaa Gadallah, Diaa Mohasseb, Nahla M. Gaballah, Abeer K. El Zohiery, Mohammed Hassan, Maha El Gaafary, Waleed Hassan, Mohamed Mortada, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Fatma H. El Nouby, Sally Saber and Salwa Galal
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:38
    Content type: Correction Published on:

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:30

  3. Resilience is the process of adjusting successfully in the face of adversity, trauma, threats, or severe stress, such as serious health problems. It is one of the factors that affect recovery from psychiatric ...

    Authors: Zahraa Nour Eldine Ismail, Mohamed Ahmed Hefny and Ahmed Elarabi Hendi
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:37
    Content type: Research Published on:

  4. Macrophage activation syndrome (MAS) is a severe life-threatening hyperinflammatory state with uncontrolled activation and proliferation of macrophages and T-lymphocytes. MAS has variable causes and risk facto...

    Authors: H. Lotfy, M. H. Abu-Zaid, S. Salah, M. El Gaafary, H. Abdulhady, H. Salah, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa, G. El Deriny…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:36
    Content type: Research Published on:

  5. Authors: Y. El Miedany, S. Salah, H. Lotfy, M. El Gaafary, H. Abdulhady, H. Salah, S. I. Nasef, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:35
    Content type: Correction Published on:

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:27

  6. Authors: Yasser El Miedany, Naglaa Ali Gadallah, Mona Mansour, Maha El Gaafary, Mohamed Mortada, Mervat Eissa, Mohammed Hassan, Waleed Hassan, Samar Abdelhamed Tabra, Nermeen Foad, Rehab Ali, Basma Medhat, Yasmin Adel, Rasha Ghaleb, Nourhan Elkaraly, Sally Saber…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:34
    Content type: Correction Published on:

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:28

  7. Systemic lupus erythematosus (SLE) is a chronic autoimmune multisystem dihe criteria for SLE according to thsease that mainly affects females of childbearing age. SLE still possesses risks during pregnancy tha...

    Authors: Wafaa K. Makarm, Rabab S. Zaghlol and Lobna I. Kotb
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:33
    Content type: Research Published on:

  8. We aimed to provide up-to-date, evidence-based and consensus-based recommendations for Treat-to-Target management of psoriatic arthritis (PsA) and associated clinical manifestations.

    Authors: Yasser El Miedany, Maha El Gaafary, Naglaa GadAllah, Mona Mansour, Nihal Fathy, Waleed Hassan, Mohamed Mortada, Salwa Galal, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Rehab Ali, Basma Medhat, Gehan El Olemy, Yasmin Adel, Rasha Ghaleb…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:32
    Content type: Research Published on:

  9. DEXA scan could be unavailable at some health centers, and radiologic examination of the mandible and oral cavity is considered more commonly used radiologic test that can predict, diagnose, or even follow-up ...

    Authors: Mounir Serage El-Din, Hesham Mohamed Farouk, Raghdaa Mohamed Teleb and Nashwa Ismail Hashaad
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:31
    Content type: Research Published on:

  10. Because of the subjective character of symptoms, absence of a diagnostic test, modest response to treatments, and, at times, patient reports of important functional disability, fibromyalgia remains a challenge...

    Authors: Yasser El Miedany, Naglaa Gadallah, Diaa Mohasseb, Nahla M. Gaballah, Abeer K. El Zohiery, Mohammed Hassan, Maha El Gaafary, Waleed Hassan, Mohamed Mortada, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Fatma H. El Nouby, Sally Saber and Salwa Galal
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:30
    Content type: Research Published on:

    The Correction to this article has been published in Egyptian Rheumatology and Rehabilitation 2022 49:38

  11. Interleukin-17 (IL-17) is a cytokine that promotes activation of multiple catabolic pathways resulting in cartilage and tissue damage. It has features making it increasingly attractive as a biological marker, ...

    Authors: Hoda M. Abdel-Naby, Sarah S. El-Tawab, Mohamed M. Rizk and Nesrin A. Aboeladl
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:29
    Content type: Research Published on:

  12. New therapies, management approaches, and evidence regarding the management of gout have become available over the past years. This triggered the need for an updated recommendation for gout management. Through...

    Authors: Yasser El Miedany, Naglaa Ali Gadallah, Mona Mansour, Maha El Gaafary, Mohamed Mortada, Mervat Eissa, Mohammed Hassan, Waleed Hassan, Samar Abdelhamed Tabra, Nermeen Foad, Rehab Ali, Basma Medhat, Yasmin Adel, Rasha Ghaleb, Nourhan Elkaraly, Sally Saber…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:28
    Content type: Research Published on:

    The Correction to this article has been published in Egyptian Rheumatology and Rehabilitation 2022 49:34

  13. These updated guidelines aimed to provide appropriate and convenient guidelines for the treatment of various types of juvenile idiopathic arthritis (JIA).

    Authors: Y. El Miedany, S. Salah, H. Lotfy, M. El Gaafary, H. Abdulhady, H. Salah, S. I. Nasef, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:27
    Content type: Research Published on:

    The Correction to this article has been published in Egyptian Rheumatology and Rehabilitation 2022 49:35

  14. Idiopathic inflammatory myopathies (IIM) are a disease complex that encompasses several distinctly acquired muscle illnesses. Anti-synthetase syndrome is a subset of IIM that is characterized by the presence o...

    Authors: Zahraa Nour Eldine Ismail and Elham Azmy Abdulkader Abdellatif
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:26
    Content type: Case Report Published on:

  15. Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation and joint destruction that eventually induces severe disability. Inflammation is the key determinant and primary underl...

    Authors: Abd Elatif Ahmed Gaballah, Noha Abdelhalim Elsawy, Wessam Mohamed El Gendy, Ahmed Hafez Afifi and Maha Saeid Mahmoud Hanafi
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:25
    Content type: Research Published on:

  16. Chronic back pain is a common health complaint among university students. A subset of chronic back pain patients suffer from increased pain sensitivity, a process termed central sensitization. Chronic pain is ...

    Authors: Maha E. Ibrahim and Mohamed A. Hefny
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:24
    Content type: Research Published on:

  18. Carpal tunnel syndrome (CTS) is caused by compression of the median nerve at the wrist level and the most frequent entrapment neuropathy in the upper limb. It can be treated with surgical or non-surgical metho...

    Authors: Poornanand Goru, George C. Butaliu, Gopalkrishna G. Verma, Syed Haque, Abubakar Mustafa and Ashok Paul
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:21
    Content type: Research Published on:

  19. Hemophilic arthropathy results in pain, deformity, and disability with severe impairments, activity limitation, and thus productivity loss. Also patterns of treatment interfere with patients’ life, so the qual...

    Authors: Hoda M. Hassab, Hany R. Saad and Hayam M. Abdel Ghany
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:22
    Content type: Research Published on:

  20. Osteonecrosis of both shoulders and hips is a rare presentation of primary antiphospholipid syndrome. A female patient aged 23 years old with no systemic diseases has her only complaint which was pain and limi...

    Authors: Aya El Shintenawy, Soha Khallaf, Esraa El Shentenawy and Ali El Deeb
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:20
    Content type: Case Report Published on:

  21. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with variable clinical manifestations that can affect various organs and tissues. Estrogen is an important element that performs a vital rol...

    Authors: Samia M. Abdel-Monem, Abdel Wahab Sh. E. El-Brashy, Waleed A. Hassan, Omnia A. Abdullah and Dalia H. Almallah
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:19
    Content type: Research Published on:

  22. Primary osteoarthritis is considered one of the most common and the most studied musculoskeletal disorder. Nevertheless, the risk factors remain unclear. A disintegrin and metalloproteinase with thrombospondin...

    Authors: Noha Abdelhady Abdelsadek Mostafa, Ibrahim Khalil Ibrahim, Neveen Lewis Mikhael and Emmanuel Kamal Aziz Saba
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:18
    Content type: Research Published on:

  23. During COVID-19 disease era, there is an accelerated demand for hydroxychloroquine since it was suggested by some centers as potential therapy for COVID-19 which has led to diminished supplies for patients wit...

    Authors: Mohammed Hassan Abu-Zaid, Hany M. Aly, Abdelhafeez Moshrif, Doaa E. Abdeldaim and Nehal El-Ghobashy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:17
    Content type: Research Published on:

  24. Systemic lupus erythematosus (SLE) is a chronic autoimmune illness defined by involvement of several systems and a variety of clinical symptoms among them the neuropsychiatric manifestations. The purpose of th...

    Authors: Ahmed Shaaban, Manal Tayel, Eman Hassan, Medhat Salah, Mohamed Ibrahim and Walaa Said
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:15
    Content type: Research Published on:

  25. Osteoarthritis is a degenerative joint disease marked by structural changes in the joint. Radiological evaluation can be used to assess structural changes. Pain, inflammation, and stiffness are common clinical...

    Authors: Naylan Fayez Wahba Khalil, Sherine El-sherif, Mowaffak Moustafa Abd El Hamid, Rehab Elnemr and Raghda Saad Zaghloul Taleb
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:16
    Content type: Research Published on:

  26. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are a group of small vessel vasculitides characterized by necrotizan vasculitis and inflammation. The phenotypes of AAV include microsc...

    Authors: A. Kocaaga and M. Kocaaga
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:14
    Content type: Review Published on:

  28. Evaluation of disease activity in systemic lupus erythematosus (SLE) patients is important for modulating the therapeutic plan and decreasing organ damage. Autoantibodies are important serological biomarkers i...

    Authors: Sahar Abdel-Rahman Elsayed, Heba Maher Kamaly and Mohamed Ali Esmail
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:8
    Content type: Research Published on:

  29. This study aimed to assess the association of disease activity with the presence of comorbidities in patients with rheumatoid arthritis, using the Akita Orthopedic Group on Rheumatoid Arthritis (AORA) registry...

    Authors: Takanori Miura, Naohisa Miyakoshi, Takeshi Kashiwagura, Hiroyuki Tsuchie, Yusuke Sugimura and Yoichi Shimada
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:7
    Content type: Research Published on:

  30. Systemic sclerosis is a complex multi-systemic autoimmune disease with a wide range of its clinical manifestations; many systemic sclerosis (SSc) patients develop musculoskeletal manifestations during their co...

    Authors: Sally A. El-Leithy, Rasha M. Hammoda, Amal I. Othman and Nermin H. El-Gharbawy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:13
    Content type: Research Published on:

  31. Familial Mediterranean Fever (FMF) is a periodic auto-inflammatory disease with multiple systemic manifestations. This study aims to describe the various musculoskeletal and neurological manifestations in a co...

    Authors: Mohamed H. Ahmed, Amira M. Ibrahim, Salma M. Ragab and Ayah M. Mahros
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:6
    Content type: Research Published on:

  32. Post-coronavirus disease (COVID-19) syndrome is defined as the persistence of symptoms for more than 3 to 12 weeks after infection with the COVID-19 virus that cannot be attributed to another etiology. This st...

    Authors: Dalia Mohamed Gamal, Rehab Ali Ibrahim and Sara Farid Samaan
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:12
    Content type: Research Published on:

  33. Adenosine signaling is now an accepted explanation for the therapeutic mechanism of Methotrexate (MTX) in rheumatoid arthritis (RA). Adenosine receptors categorized into four subclasses: adenosine A1 receptor ...

    Authors: Nivine Fathi Darwish, Samar Abd Alhamed Tabra, Nivin Naeem Baiomy, Heba A. Mahmoud, Reham A. Mariah and Shymaa Ahmed Hablas
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:5
    Content type: Research Published on:

  34. Despite a broad spectrum of effective anti-osteoporosis therapies and a growing number of older adults worldwide, the number of people receiving appropriate secondary fracture prevention is not yet optimum or ...

    Authors: Naglaa Gadallah and Yasser El Miedany
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:11
    Content type: Review Published on:

  35. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s43166-020-00041-2.

    Authors: Eman A. Baraka, Sami A. Egilla, Gamal A. Hamad, Maiada A. Khalil, Shereen H. Ahmed and Mona M. Elbehisy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:10
    Content type: Retraction Note Published on:

  36. Sleep disturbance is closely related to inflammation and pain. Good sleep quality is essential for patients’ psychological and physical states as well as their quality of life. The aim of this study was to det...

    Authors: Rasha M. Fawzy, Samia M. Abdel-Monem, Abdel-Wahab S. El-Brashi and Asmaa A. Mohamed
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:4
    Content type: Research Published on:

  37. Thrombotic consequences have been reported in COVID-19-infected patients, especially those who are critically ill. Multiple studies have tested antiphospholipid antibodies (aPLs) among COVID-19 patients, but t...

    Authors: Omaima Ibrahim Badr, Wael Aly Elrefaey, Mohammed Hassan Abu-Zaid and Samah Hamdy Elmedany
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:3
    Content type: Research Published on:

  38. Through the disease course, different prognostic factors have been addressed in patients with SLE admitted to intensive care unit. For instance, higher disease activity on admission, recent immunosuppressive t...

    Authors: Shimaa Mostafa Abdelwhab, Lobna Ismaeil Kotb, Ghada Sameer and Ghada Dawa
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:2
    Content type: Research Published on:

  39. Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with more than one organ involvement. Kidney is the foremost commonly affected one. Gelsolin is a protein that induces depolymerization of ac...

    Authors: Ghada M. Mosaad, Samia M. Abdel moneam, Amal F. Soliman, Seham G. Ameen and Arwa S. Amer
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:1
    Content type: Research Published on:

  40. The full etiology of RA remains unclear; in addition to the contributions of infectious, hormonal, and environmental factors, several lines of evidence have suggested that the disease has a genetic basis. The ...

    Authors: Rehab A. Sallam, Bassant S. Saad, Mona A. El Wassefy and Basma A. EL Kady
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:47
    Content type: Research Published on:

  41. The proportion of older people in the total population has increased in Turkey as well as worldwide. As life expectancy rises, the increasing prevalence of rheumatic diseases poses major problems in the elderl...

    Authors: Tuba Erdem Sultanoğlu, Safinaz Ataoğlu, Burcu Avşar and Ömer Faruk Merkür
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:40
    Content type: Research Published on:

  42. Rheumatoid arthritis (RA), an autoimmune disorder, characterized by systemic inflammation and swollen joints, establishes itself as a critical threat. A pro-inflammatory cytokine TNF-α is a well-known driver o...

    Authors: Pulak Kanti Palit, Ashekul Islam, Md Syeed Al Habib, Abu Syed Mohammed Mujib, Joyonti Datta, Bahni Chakraborty, Suman Dhar, Dhiman Chowdhury, Md Faisal Fahad Chowdhury, Mohammad Shawkat Ali, Arfana Yesmin, Mohammod Johirul Islam, Nishat Akther, Abdullah Al Mamun, Khairul Islam and Pradip Kumar Nath
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:50
    Content type: Research Published on:

  43. Rheumatoid arthritis (RA) is an autoimmune inflammatory disease. It is characterized by an inflammatory polyarthritis that preferentially affects the small joints leading to joint damage and eventual deformity...

    Authors: Hanaa Maher Abdeen, Ola Mohammad Gharbia, Sherine Abdel Rahman Abdel Karim Bassiouni, Maysaa El Sayed Zaki, Hazem Abdullah and Heba Kamal Morsi
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:39
    Content type: Research Published on:

  44. Rheumatoid arthritis (RA) is a common disabling joint disease affecting both males and females. Sexual dysfunction (SD) is a common association with RA. The aim of this work was to study the prevalence and pre...

    Authors: Mohamed Azab, Maii Abdelraheem Abdellatif and Mai Mohamed Abdelnaby
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:38
    Content type: Research Published on:

  45. Toll-like (TLRs) play a crucial role in both adaptive and innate immunity. The aim of the present study was to assess the association of TLR5-rs5744168, TLR9-rs187084, and TLR9-rs352140 single nucleotide polym...

    Authors: Ola Mohammad Gharbia, Sherine Abdel Rahman Bassiouni, Maysaa El Sayed Zaki, Shimaa Mohsen El-Beah, Manal Mohamed El-Desoky, Eman Adel Elmansoury and Mostafa Abdelsalam
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:49
    Content type: Research Published on:

  46. A major problem in surgery of peripheral nerve injuries of the upper extremities is the unpredictable final outcome. More insight and understanding of the proper methods of outcome assessment and the prognosti...

    Authors: Nahla Ahmed Hassan, Noha Abdelhalim Elsawy, Hesham Hussien Kotb, Mowaffak Mostafa Abd El-Hamid, Wafaa Samir El Emairy and Hassan Mahmoud Kholosy
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:48
    Content type: Research Published on:

  47. Cerebral palsy (CP) is the most prevalent severe motor disability among children. The aim of this work was to assess autonomic dysfunction in children with cerebral palsy clinically and electrophysiologically.

    Authors: Hanan G. Azouz, Ali M. AbdelMohsen, Hayam M. Abdel Ghany and Rana M. Mohamed
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:45
    Content type: Research Published on:

  48. Rheumatoid arthritis (RA) is a disease of an autoimmune nature that involves all types of joints structures and manifested by chronic joints inflammations and thus their erosions and damage. Dickkopf-1 (DKK-1)...

    Authors: Dina A. Ali, Doaa Mohamed Esmail, Haidy Ali Mohammed, Reham Lotfy Yonis and Radwa Mahmoud El-Sharaby
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:42
    Content type: Research Published on:

  49. The advent of novel biologic agents for the treatment of rheumatoid arthritis (RA) has proven to be highly productive. Nonetheless, high cost, side effects, and unresponsiveness to these agents dictates the as...

    Authors: Rania Abd El-Hamid El-Kady, Ayah Fathy, Talaat Othman and Eman Hafez
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:46
    Content type: Research Published on:

  50. Mixed urinary incontinence (MUI) is a common underreported problem among females; it has a major effect on patients’ quality of life. Treatment may be difficult since a single modality cannot be enough to alle...

    Authors: Nehad Mohamed Elshatby, Mohamed Hassan Imam, Mohamed Shafik Shoukry, Marwa Mohamed Hassan and Emmanuel Kamal Aziz Saba
    Citation: Egyptian Rheumatology and Rehabilitation 2021 48:41
    Content type: Research Published on:
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