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  1. The pro-inflammatory cytokine, interleukin 16 (IL-16), has been shown to be secreted in low levels in knee osteoarthritis (KOA). The aim of the study was to examine the relationship between IL-16 polymorphisms...

    Authors: Eman Abdel Razek Hafez, Reham Magdi Shaat, Ola Mohamed Gharbia, Shereen Aly Machaly, Ola Ali El- Emam, Nermin Youssef Abo El –Kheir, Narmin Saied, Alaa Abo Nour, Sherif Elkhanishy, Rasha Hassan and Heba El Shehawy
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:12
  2. Diabetic retinopathy is now recognized as a neurovascular in lieu of a microvascular complication. Visual evoked potentials (VEPs) are greatly valuable in detecting early diabetic retinal functional changes be...

    Authors: Sarah Sayed El-Tawab, Ibrahim Khalil Ibrahim, Magdy Helmy Megallaa, Rania Mohamed Abdel Mgeed and Wafaa Samir Elemary
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:11
  3. Antiphospholipid syndrome (APS) is one of the most frequent forms of acquired thrombophilia and is associated with an increased risk of stroke, heart attack, pulmonary embolism, and miscarriage in young women....

    Authors: Ahmed A. G. Ibrahim, Hesham W. E. Shadi, Awab A. Y. Elamin and Hoda E. Draz
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:10
  4. The proportion of the late-onset forms of disease is growing in rheumatoid arthritis (RA) population. Concerns about comorbidities and drug adverse events lead to delay or ineffective treatment in these patien...

    Authors: Esra Dilsat Bayrak and Ilknur Aktas
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:8
  5. Despite the associated high prevalence of morbidity and mortality, osteoporotic fragility fractures remain underdiagnosed and undertreated. Furthermore, those who sustain a fragility fracture are at imminent r...

    Authors: Yasser El Miedany, Mona M. Hasab El Naby, Mohammed Hassan Abu-Zaid, Safaa Mahran, Mervat Eissa, Heba Gamal Saber, Samar Abdalhamed Tabra, Rehab Ali Ibrahim, Salwa Galal and Walaa Elwakil
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:7
  6. Children with hemophilia have serious, recurrent joint bleeding that causes disabilities. Regular factor VIII concentrate replacements have not yet completely stopped intra-articular subclinical hemorrhages an...

    Authors: Omar Ahmed M. N. Saboony, Mona Abdullah El Sebaie, Dalia Mohamed Ezz El Din El Mikkawy, Iman Ahmed Mohamed Ragab and Hossam Salaheldin Abdelmohsen Labib
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:6
  7. Minimally invasive cardiac surgery (MICS) has steadily become more and more popular. MICS is less invasive and has a faster return to normality after surgery. Patients who had MICS continue to exercise more fr...

    Authors: Hossam salaheldin Abdelmohsen Labib, Shereen I. Fawaz, Mohamed El Ghanam and Moustafa Gamal ELBarbray
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:5
  8. Intervertebral disc degeneration (IVD) is a main underlying cause for low back pain (LBP). Oswestry Disability Index (ODI) is a valuable tool used to measure patient’s low back functional outcome. Our aim is t...

    Authors: Aliaa Omar El-Hady, Soad Said El Molla, Sherine Ibrahim Elwan and Rehab Ali Ibrahim
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:4
  9. There is an evidence-practice gap in osteoarthritis (OA) management which has caused several patients living with the disease are receiving suboptimal medical care. Though there are several guidelines and trea...

    Authors: Yasser El Miedany and Walaa Elwakil
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:3
  10. Behcet’s disease (BD) does not have specific laboratory finding or pathological physical examination sign, and only few studies have investigated Neutrophil to lymphocyte ratio (NLR), platelets to lymphocytes ...

    Authors: Zahraa I. Selim, Naima M. Mostafa, Esraa O. Ismael and Doaa Kamal
    Citation: Egyptian Rheumatology and Rehabilitation 2023 50:1
  11. Systemic lupus erythematosus is a multifaceted chronic relapsing autoimmune disease of unknown etiology. The disease has always been a serious diagnosis in women being a multisystem pathology that is classical...

    Authors: Reem Hamdy A. Mohammed, Hassan Mumtaz, Abdul Basit Sangah, Shazia Saleem Shaikh, Noreen Nasir and Sidra Jabeen
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:67
  12. Diabetic peripheral neuropathy (DPN) is a common microvascular complication in type 2 diabetes mellitus (T2DM). The nerve fibers injury is caused by the interaction between metabolic and vascular factors. Vasc...

    Authors: Mai Hesham Badrah, Talaat Abdelfattah Abdelaaty, Salma Alaa Eldin Imbaby, Yousra Hisham Abdel-Fattah, Walid Mohamed Silim and Amr Yosry El Feky
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:66
  13. Coronavirus disease 2019 (COVID-19) infection is linked to high levels of inflammatory cytokines and prolonged immobilization; furthermore, corticosteroid treatment leads to increased bone loss and resorption....

    Authors: Samah Hamdy Elmedany, Omaima Ibrahim Badr, Mohammed Hassan Abu-Zaid and Samar Abd Alhamed Tabra
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:64
  14. Methotrexate (MTX) is an anchor drug used for the treatment of rheumatoid arthritis (RA); hence, understanding the reasons for MTX discontinuation in RA can help improve its treatment. Therefore, this study ai...

    Authors: Hiroko Nagafuchi, Yutaka Goto, Tomofumi Kiyokawa and Kimito Kawahata
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:63
  15. Carpal tunnel syndrome (CTS) is known as one of the most common neurological extra-articular manifestations in rheumatoid arthritis (RA) patients. Studies on CTS in RA depend mostly on electrophysiological ass...

    Authors: Wafaa Mahmoud, Mona Mansour Hassab El-Naby and Ahmed Abdellatif Awad
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:62
  16. The overarching goal of treating osteoporotic patients is to reduce the incidence of fractures, yet interventions that support early detection of osteoporosis and prevention of osteoporotic fractures are under...

    Authors: Yasser El Miedany, Naglaa Ali Gadallah and Mathias Toth
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:61
  17. We aimed at screening for subclinical psoriatic arthritis (PsA) among psoriatic patients without musculoskeletal complaints using ultrasonography of the lower limbs and finding the best predictor for its devel...

    Authors: Sherine Mahmoud El-Sherif, Tamer Gaweesh and Rasha Mahmoud Genedy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:60
  18. Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis. Its severity ranges from indolent disease to fulminant that may cause death. With treatment, remission is seen in more than 80% of cases, a...

    Authors: Sara Safari, Samira Alesaeidi, Bahram Pakzad and Sina Abbaspour
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:59
  19. Psoriatic arthritis (PsA) which affects 6–42% of psoriasis patients is the most common extra-cutaneous manifestation of the psoriasis disease. Enthesitis may be considered as a sign of increased disease burden...

    Authors: Dalia S. Fahmi, Wafaa K. Makarm and Rabab S. Zaghlol
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:58
  20. Martin–Gruber anastomosis (MGA) is one of the most common anomalous innervations of the upper limb. It may alter the usual clinical picture and electrophysiological characteristics of median nerve (MN) injury ...

    Authors: Hager El-Shehawy Mohamed, Samia M. Abdel-Monem, Gamal Abdel-Ghafaar Hammad and Marwa Yahia Mahgoub
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:57
  21. Busy rheumatologists, and busy patients as well as policy makers, require accurate, succinct, transparent, easily digested summaries of evidence and recommendations for management. Our objective was to develop...

    Authors: Yasser El Miedany, Mohammed Hassan Abu-Zaid, Maha El Gaafary, Mona Mansour, Nihal Fathy, Waleed Hassan, Mohamed Mortada, Mervat Eissa, Samar Abdelhamed Tabra, Salwa Galal, Nermeen Foad, Rehab Ali Ibrahim, Basma Medhat, Gehan El Olemy, Yasmin Adel, Rasha Ghaleb…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:56
  22. Severe coronavirus disease 2019 (COVID-19) infections are associated with increased levels of C-reactive protein (CRP) and several pro-inflammatory cytokines leading to cytokine storm. Vitamin D has been prove...

    Authors: Caroline S. Morad, Reem A. Habeeb, Esraa T. Yassin and Salma A. Khalil
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:55
  23. Musculoskeletal ultrasound is a useful, noninvasive tool to detect anatomical damage in the hyaline cartilage, synovial tissue, and tendons of individuals with asymptomatic hyperuricemia. This study aimed to d...

    Authors: Nashwa Ismail Hashaad, Sahar Saad Ganeb, Saddam A. A. Hassan, Shimaa Hamdeen Mohamed and Noha Hosni Ibrahim
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:54
  24. Electrodiagnostic tests  (EDXTs) have been considered the gold standard method for the diagnosis of tarsal tunnel syndrome (TTS); however, definitive tests has not yet been discovered. Our aim was to develop n...

    Authors: Mona M. Hasab ElNaby, Amr Farouk Abdel Rahman and Rehab Ali Ibrahim
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:53
  25. This is a Clinical Practice Guideline update released by the Egyptian Academy of Bone Health and Metabolic Bone Diseases. It does not replace the clinical practice guidelines published for the treatment of ost...

    Authors: Yasser El Miedany, Naglaa Ali Gadallah, Mathias Toth, Waleed Hassan, Maha Elgaafary, Mohamed Hassan, Mervat Eissa, Sally Saber, Walaa Elwakil and Safaa Mahran
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:52
  26. Cranial neuropathies occur in 3 to 14% of diabetic patients. Motor conduction study of the facial nerve and blink reflex study are electrophysiologic techniques used to assess the facio-trigeminal pathway in d...

    Authors: Gihan Abd El Fattah Tawfik, Hussein El Moghazy Sultan, Gihan Abd El Lattif Younis and Wafaa Samir El Emairy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:51
  27. Functional obstructed defecation is a common anorectal problem among adult population. The objective was to compare the short-term efficacy of biofeedback pelvic floor muscle training versus transcutaneous pos...

    Authors: Emmanuel Kamal Aziz Saba and Mervat Sheta Elsawy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:49
  28. There is limited and conflicting information on Fgf23 levels and their relationship with bone loss and disease activity in rheumatoid arthritis (RA). The aim of this study was to compare Fgf23 levels in RA pat...

    Authors: Direnç Şerif Çelik, Koray Ayar, Selime Ermurat and Yasemin Üstündağ
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:50
  29. Lupus nephritis (LN) affects a substantial number of the patients living with Systemic lupus erythematosus (SLE), representing a major cause of morbidity and mortality. Patients with lupus nephritis should be ...

    Authors: Yasser El Miedany, Nadia Salah Kamel, Mohammed Hassan Abu-Zaid, Khaled El Hadidi, Geilan Abdelmoneim Mahmoud, Eman Sarhan, Maha El Gaafary, Ahmed Abdel-Nasser, Esam M. Abualfadl, Atef Abdel Azim, Nihal Ahmed Fathi, Abir Mokbel, Waleed Hassan, Samar Abd Alhamed Tabra, Mervat Eissa, Mohamed Mortada…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:48
  30. Nephritis is known to be one of the most serious complications of lupus and a strong predictor of poor outcome. This study was carried out aiming at setting up an up-to-date recommendation for the management o...

    Authors: Yasser El Miedany, Nadia Salah Kamel, Mohammed Hassan Abu-Zaid, Khaled El Hadidi, Geilan Abdelmoneim Mahmoud, Maha El Gaafary, Eman Sarhan, Ahmed Abdel-Nasser, Esam M. Abualfadl, Atef Abdel Azim, Nihal Ahmed Fathi, Abir Mokbel, Waleed Hassan, Mervat Eissa, Samar Abd Alhamed Tabra, Mohamed Mortada…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:47
  31. Erythema elevatum diutinum (EED) is a rare disease with unknown etiology, various presentations, broad spectrum of underlying conditions, and unified pathology. So, every case of it merits further investigatio...

    Authors: Fakhreddin Sabooniha
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:45
  32. SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare, heterogeneous, self-limited disease of unknown etiology. It involves progressive bone and joint damage, and skin and bone les...

    Authors: Viviana Parra-Izquierdo, Hector Cubides, Viviana Rivillas, Juan Sebastián Frías-Ordoñez, Sergio Mora and Joerg Ermann
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:44
  33. The fibrinogen to albumin ratio (FAR) has risen to prominence as a novel biomarker for various conditions, including systemic inflammation. Therefore, this study aims to assess the role of FAR in ankylosing sp...

    Authors: Noha Hosni Ibrahim, Mounir Serag-El Deen El Hanafy, Abdel Wahab Shams-El Deen El Brashy and Enas Adel Abd-Elmonem
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:43
  34. Research on the COVID-19 vaccination in patients with underlying rheumatic disorders in pediatric age is lacking. We studied possible adverse events of the mRNA BNT162b2 vaccine against SARS-CoV-2 (Pfizer-BioN...

    Authors: Abobakr A. Abdelgalil, Reima A. Bakry and Mohammed A. Muzaffer
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:42
  35. Peripheral nervous system and the central nervous system involvement in systemic lupus erythematosus (SLE) patients are one of the major causes of morbidity and mortality. The aim of this work was to study the...

    Authors: Alaa M. Thabet, Sara A. Elnwam, Jaidaa F. Mekky, Hayam M. Abdelghany and Hanan M. Fathy
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:41
  36. We aimed to provide a consensus, evidence-based recommendations for the diagnosis, evaluation, and treat-to-target management of children living with FMF.

    Authors: S. Salah, H. Lotfy, M. H. Abu-Zaid, M. El Gaafary, H. Abdulhady, H. Salah, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa, G. El Deriny…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:39
  37. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yasser El Miedany, Naglaa Gadallah, Diaa Mohasseb, Nahla M. Gaballah, Abeer K. El Zohiery, Mohammed Hassan, Maha El Gaafary, Waleed Hassan, Mohamed Mortada, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Fatma H. El Nouby, Sally Saber and Salwa Galal
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:38

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:30

  38. Resilience is the process of adjusting successfully in the face of adversity, trauma, threats, or severe stress, such as serious health problems. It is one of the factors that affect recovery from psychiatric ...

    Authors: Zahraa Nour Eldine Ismail, Mohamed Ahmed Hefny and Ahmed Elarabi Hendi
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:37
  39. Macrophage activation syndrome (MAS) is a severe life-threatening hyperinflammatory state with uncontrolled activation and proliferation of macrophages and T-lymphocytes. MAS has variable causes and risk facto...

    Authors: H. Lotfy, M. H. Abu-Zaid, S. Salah, M. El Gaafary, H. Abdulhady, H. Salah, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa, G. El Deriny…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:36
  40. Authors: Y. El Miedany, S. Salah, H. Lotfy, M. El Gaafary, H. Abdulhady, H. Salah, S. I. Nasef, E. Abd El-Latif, Y. Farag, M. Eissa, S. Esam Maher, A. Radwan, Amira T. El-Shanawany, B. M. Medhat, D. El Mikkawy, D. M. Mosa…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:35

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:27

  41. Authors: Yasser El Miedany, Naglaa Ali Gadallah, Mona Mansour, Maha El Gaafary, Mohamed Mortada, Mervat Eissa, Mohammed Hassan, Waleed Hassan, Samar Abdelhamed Tabra, Nermeen Foad, Rehab Ali, Basma Medhat, Yasmin Adel, Rasha Ghaleb, Nourhan Elkaraly, Sally Saber…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:34

    The original article was published in Egyptian Rheumatology and Rehabilitation 2022 49:28

  42. Systemic lupus is a chronic autoimmune multisystem disease that mainly affects females of childbearing age. SLE still possesses risks during pregnancy that lead to poor maternal and fetal outcomes. The objecti...

    Authors: Wafaa K. Makarm, Rabab S. Zaghlol and Lobna I. Kotb
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:33

    The Correction to this article has been published in Egyptian Rheumatology and Rehabilitation 2023 50:54

  43. We aimed to provide up-to-date, evidence-based and consensus-based recommendations for Treat-to-Target management of psoriatic arthritis (PsA) and associated clinical manifestations.

    Authors: Yasser El Miedany, Maha El Gaafary, Naglaa GadAllah, Mona Mansour, Nihal Fathy, Waleed Hassan, Mohamed Mortada, Salwa Galal, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Rehab Ali, Basma Medhat, Gehan El Olemy, Yasmin Adel, Rasha Ghaleb…
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:32
  44. DEXA scan could be unavailable at some health centers, and radiologic examination of the mandible and oral cavity is considered more commonly used radiologic test that can predict, diagnose, or even follow-up ...

    Authors: Mounir Serage El-Din, Hesham Mohamed Farouk, Raghdaa Mohamed Teleb and Nashwa Ismail Hashaad
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:31
  45. Because of the subjective character of symptoms, absence of a diagnostic test, modest response to treatments, and, at times, patient reports of important functional disability, fibromyalgia remains a challenge...

    Authors: Yasser El Miedany, Naglaa Gadallah, Diaa Mohasseb, Nahla M. Gaballah, Abeer K. El Zohiery, Mohammed Hassan, Maha El Gaafary, Waleed Hassan, Mohamed Mortada, Mervat Eissa, Samar Abdelhamed Tabra, Nermeen Foad, Fatma H. El Nouby, Sally Saber and Salwa Galal
    Citation: Egyptian Rheumatology and Rehabilitation 2022 49:30

    The Correction to this article has been published in Egyptian Rheumatology and Rehabilitation 2022 49:38

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