Table 1 The key clinical questions

1. What is the aim of this guideline?

2. Who are the targeted audience?

3. What is the classification of scleroderma?

4. What are the benefits of classification or stratification of Systemic Sclerosis?

5. How to evaluate and follow-up systemic sclerosis patient?

6. How to screen for organ involvement in SSc?

7. What are the general recommendations in the management of early SSc?

8. How to manage organ-specific affection in SSC?

9. What is the non-pharmacological management of systemic sclerosis?

10. What is the risk of malignancies in systemic sclerosis patient?

11. What are the serious complications and prognosis of systemic sclerosis?