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Primary Sjögren’s syndrome with polymyositis, a rare amalgamation

Abstract

Sjögren’s syndrome is characterized by diminished lacrimal and salivary gland secretory function. This disorder is not strictly confined to the exocrine glands and its manifestations may extend to extraglandular sites, such as the lungs, kidneys, reticuloendothelial system, and the musculoskeletal system. Although muscular manifestations are very common with Sjögren’s syndrome, true myopathy is very rare. Here, we report a case of a 45-year-old woman who presented with complaints of bilateral progressive weakness of upper and lower limbs associated with difficulty in neck holding with a history of dryness of the mouth and the eyes. The diagnosis of polymyositis associated with Sjögren’s syndrome was established on the basis of clinical picture and diagnostic tests. True polymyositis is very rare in primary Sjögren syndrome and there are scarcely any cases of primary Sjögren’s syndrome with polymyositis reported in the literature.

References

  1. Uxholm P, Manthorpe R, Prause JA. Polyclonal B-cell activiation is related to exocrine manifestations of primary Sjögren’s syndrome. J Autoimmun 1989; 2:515–520.

    Article  Google Scholar 

  2. Martinez-Lavin M, Vaughan JH, Tan EM. Autoantibodies and the spectrum of Sjögren’s syndrome. Ann Intern Med 1979; 91:185–190.

    CAS  Article  Google Scholar 

  3. Shiboski CH, Shiboski SC, Seror R, et al. 2016 American College of Rheumatology/European League against Rheumatism classification criteria for primary Sjögren’s syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis 2017; 76:9–16.

    Article  Google Scholar 

  4. Saraux A, Per J-O, Devauchelle-Pensec V. Treatment of primary Sjögren syndrome. Nat Rev Rheumatol 2016; 12:456–471.

    CAS  Article  Google Scholar 

  5. Mastaglia FL, Ojeda VJ. Inflammatory myopathies. Part I. Ann Neurol 1985; 17:21527.

    Google Scholar 

  6. Hietaharju A, Yli-Kerttula U, Hakkinen V, Frey H. Nervous system manifestations in Sjögren’s syndrome. Acta Neurol Scand 1990; 81: 144–152.

    CAS  Article  Google Scholar 

  7. Muller K, Oxholm P, Hojer-Madsen M, Wiik A. Circulating IgA- and IgM rheumatoid factors in patients with primary Sjögren’s syndrome. Scand J Rheumatol 1989; 18:29–31.

    CAS  Article  Google Scholar 

  8. Kraus A, Cifuentes M, Villa AR, Jakez J, Reyes J, Alarcon-Segovia D. Myositis in primary Sjögren’s syndrome. Report of 3 cases. J Rheumatol 1994; 21:649–653.

    CAS  PubMed  Google Scholar 

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Correspondence to Deepak Jain MD.

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Singh, H., Jain, D., B, K. et al. Primary Sjögren’s syndrome with polymyositis, a rare amalgamation. Egypt Rheumatol Rehabil 45, 39–41 (2018). https://doi.org/10.4103/err.err_25_17

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  • DOI: https://doi.org/10.4103/err.err_25_17

Keywords

  • myopathy
  • polymyositis
  • Sjögren’s
  • syndrome