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The health-related quality of life in stroke survivors: clinical, functional, and psychosocial correlate

Abstract

Aim

The aims of this study were to examine the health-related quality of life (HRQOL) in stroke survivors attending an outpatient rehabilitation clinic and to examine the relation between some clinical variables and HRQOL.

Participants and methods

Sixty-four stroke survivors were enrolled. Demographic data were obtained using a structured questionnaire. The functional level of the patients was assessed using the Barthel Index (BI). HRQOL was measured by the short-form 36 (SF-36) and the stroke-specific quality-of-life (SSQOL) scale.

Results

Our patients’ ages ranged from 42 to 95 years (mean 60.81 years), and men represented 81.2% of the participants. Low mean scores of all the eight domains of SF-36 were found. The 12 domains of SSQOL showed different degrees of deterioration in their means. Statistically significant differences between the means of the mobility level, and upper-limb and lower-limb voluntary control with the means of both SF-36 and SSQOL were found in favor of functional independency and full control of the limbs (P < 0.05). Voluntary control of the limbs and BI showed a significant positive correlation with both SSQOL and the physical component of SF-36. Multiple regression analysis showed that the BI score, the nature of stroke, and the comorbidities are the most significant predictors of SSQOL, with P values of 0.004, 0.013, and 0.047, respectively.

Conclusion

It was concluded that HRQOL is impaired in stroke survivors, and that the functional independency level is its most significant predictor. We recommend considering the assessment of HRQOL in stroke survivors undergoing rehabilitation management as it is more relevant to the patients.

References

  1. Lavados PM, Hennis AJ, Fernandes JG, Medina MT, Legetic B, Hoppe A, et al. Stroke epidemiology, prevention, and management strategies at a regional level: Latin America and the Caribbean. Lancet Neurol 2007; 6:362–372.

    Article  PubMed  Google Scholar 

  2. Mar J, Sainz-Ezkerra M, Moler-Cuiral JA. Calculation of prevalence estimates through differential equations: application to stroke-related disability. Neuroepidemiology. 2008; 31:57–66.

    Article  PubMed  Google Scholar 

  3. Wilkinson PR, Wolfe CDA, Warburton FG, Rudd AG, Howard RS, Ross-Russell RW, Beech RR, et al. A long-term follow up of stroke patients. Stroke 1997; 28:507–512.

    Article  CAS  PubMed  Google Scholar 

  4. Bush TL, Miller SR, Golden AL, Hale WE. Self-report and medical record report agreement of selected medical conditions in the elderly. Am J Public Health 1989; 79:1554–1556.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Mahoney FD, Barthel DW. Functional evaluation: the Barthel index. Md State Med J 1965; 14:61–63.

    CAS  PubMed  Google Scholar 

  6. Scoring demonstration. Available at: http://www.sf-36.org/demos/SF-36.html. [Accessed on 2013 Jan 2].

  7. Online scoring service. Available at: http://www.sf-36.org/demos/SF-36. html [Accessed on 2013 Jan 2].

  8. Williams LS, Weinberger M, Harris LE, Biller J. Measuring quality of life in a way that is meaningful to stroke patients. Neurology 1999; 53: 1839– 1843.

    Article  CAS  PubMed  Google Scholar 

  9. Lima RCM, Teixeira-Salmela LF, Magalhaes LC, Gomes-Neto M. Psychometric properties of the Brazilian version of the Stroke Specific Quality of Life Scale: application of the Rasch model. Rev Bras Fisioter 2008; 12:149–156.

    Google Scholar 

  10. Muus I, Williams LS, Ringsberg KC. Validation of the Stroke Specific Quality of Life Scale (SS-QOL): test of reliability and validity of the Danish version (SS-QOL-DK). Clin Rehabil 2007; 21:620–627.

    Article  PubMed  Google Scholar 

  11. Ewert T, Stucki G. Validity of the SS-QOL in Germany and in survivors of hemorrhagic or ischemic stroke. Neurorehabil Neural Repair 2007; 21:161–168.

    Article  PubMed  Google Scholar 

  12. Fróes KS, Valdés MT, Lopes Dde P, Silva CE. Factors associated with health-related quality of life for adults with stroke sequelae. Arq Neuropsiquiatr 2011; 69:371–376.

    Article  PubMed  Google Scholar 

  13. Noble AJ, Schenk T. Which variables help explain the poor health-related quality of life after subarachnoid hemorrhage? A meta-analysis. Neurosurgery 2010; 66:772–783.

    Article  PubMed  Google Scholar 

  14. Carod-Artal FJ, Egido JA. Quality of life after stroke: the importance of a good recovery. Cerebrovasc Dis 2009; 27(Suppl 1):204–214.

    Article  PubMed  Google Scholar 

  15. Graham A. Measurement in stroke: activity and quality of life. In: Barnes MP, Dobkin BH, Bogusslavsky J, editors. Recovery after stroke. New York: Cambridge University Press; 2005. 135–160.

    Chapter  Google Scholar 

  16. Chou CY. Determinants of the health-related quality of life for stroke survivors. J Stroke Cerebrovasc Dis 2015; 24:655–662.

    Article  PubMed  Google Scholar 

  17. Haacke C, Althaus A, Spottke A, Siebert U, Back T, Dodel R. Long-term outcome after stroke: evaluating health-related quality of life using utility measurements. Stroke 2006; 37:193–198.

    Article  PubMed  Google Scholar 

  18. Franke CL, Van Swieten JC, Algra A, Van Gijn J. Prognostic factors in patients with intracerebral hematoma. J Neurol Neurosurg Psychiatry 1992; 55:653–657.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Kapral MK, Fang J, Hill MD, Silver F, Richards J, Jaigobin C, Cheung AM, Investigators of the Registry of the Canadian Stroke Network. Sex differences in stroke care and outcomes: results from the Registry of the Canadian Stroke Network. Stroke 2005; 36:809–814.

    Article  PubMed  Google Scholar 

  20. Paolucci S, Bragoni M, Coiro P, De Angelis D, Fusco FR, Morelli D, et al. Is sex a prognostic factor in stroke rehabilitation? A matched comparison. Stroke 2006; 37:2989–2994.

    Article  PubMed  Google Scholar 

  21. Xie J, Wu EQ, Zheng ZJ, Croft JB, Greenlund KJ, Mensah GA, Labarthe DR. Impact of stroke on health-related quality of life in the noninstitutionalized population in the United States. Stroke 2006; 37:2567–2572.

    Article  PubMed  Google Scholar 

  22. Hooi LN. What are the clinical factors that affect quality of life in adult asthmatics? Med J Malaysia 2003; 58:506–515.

    CAS  PubMed  Google Scholar 

  23. Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. J Am Soc Nephrol 2001; 12:2797–2806.

    CAS  PubMed  Google Scholar 

  24. Labiche LA, Chan W, Saldin KR, Morgenstern LB. Sex and acute stroke presentation. Ann Emerg Med 2002; 40:453–460.

    Article  PubMed  Google Scholar 

  25. Sturm JW, Donnan GA, Dewey HM, Macdonell RA, Gilligan AK, et al. Quality of life after stroke: the North East Melbourne Stroke Incidence Study (NEMESIS). Stroke 2004; 35:2340–2345.

    Article  PubMed  Google Scholar 

  26. Herrmann N, Black SE, Lawrence J, Szekely C, Szalai JP. The Sunnybrook Stroke Study: a prospective study of depressive symptoms and functional outcome. Stroke 1998; 29:618–624.

    Article  CAS  PubMed  Google Scholar 

  27. Aprile L, Piazzini DB, Bertolini C, Caliandro C, Pazzaglia C, Tonali P, Padua L. Predictive variable on disability and quality of life in stroke outpatients undergoing rehabilitation. Neurol Sci 2006; 27:40–46.

    Article  CAS  PubMed  Google Scholar 

  28. Lin KC, Fu T, Wu CY, Hsieh CJ. Assessing the stroke-specific quality of life for outcome measurement in stroke rehabilitation: minimal detectable change and clinically important difference. Health Qual Life Outcomes 2011; 9:5.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Abubakar SA, Isezuo SA. Health related quality of life of stroke survivors: experience of a stroke unit. Int J Biomed Sci 2012; 8:183–187.

    CAS  PubMed  PubMed Central  Google Scholar 

  30. Sturm JW, Donnan GA, Dewey HM, Macdonell RA, Gilligan AK, Thrift AG. Determinants of handicap after stroke: the North East Melbourne Stroke Incidence Study (NEMESIS). Stroke 2004; 35: 715– 720.

    Article  PubMed  Google Scholar 

  31. Rochette A, Desrosiers J, Norrau L. Associated between personal and environmental factors and occurrence of handicap situation following a stroke. Disabil Rehabil 2001; 23:559–569.

    Article  CAS  PubMed  Google Scholar 

  32. Carod-Artal J, Egido JA, González JL, Varela de Seijas E. Quality of life among stroke survivors evaluated 1 year after stroke: experience of a stroke unit. Stroke 2000; 31:2995–3000.

    Article  CAS  PubMed  Google Scholar 

  33. Muus I, Petzold M, Ringsberg KC. Health-related quality of life among Danish patients 3 and 12 months after TIA or mild stroke. Scand J Caring Sci2010; 24:211–218.

    Article  PubMed  Google Scholar 

  34. Díaz-Tapia V, Gana J, Sobarzo M, Jaramillo-Muñoz A, Illanes-Díez S. Estudio sobre la calidad de vida en pacientes con accidente vascular cerebral isquémico. Rev Neurol 2008; 46:652–655.

    PubMed  Google Scholar 

  35. Aprile I, Piazzini DB, Bertolini C, Caliandro P, Pazzaglia C, Tonali P, Padua L. Predictive variables on disability and quality of life in stroke outpatients undergoing rehabilitation. Neurol Sci 2006; 27:40–46.

    Article  CAS  PubMed  Google Scholar 

  36. Jönsson AC, Lindgren I, Hallstrom B, Norrving B, Lindgren A. Determinants of quality of life in stroke survivors and their informal caregivers. Stroke 2005; 36:803–808.

    Article  PubMed  Google Scholar 

  37. Lai SM, Studenski S, Duncan PW, Perera S. Persisting consequences of stroke measured by the Stroke Impact Scale. Stroke 2002; 33:1840–1844.

    Article  PubMed  Google Scholar 

  38. Addington-Hall J, Kalra L. Who should measure quality of life? BMJ 2001; 322:1417–1420.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Snoek GJ, Ijzerman MJ, Hermens HJ, Maxwell D, Biering-Sorensen F. Survey of the needs of patients with spinal cord injury: impact and priority for improvement in hand function in tetraplegics. Spinal Cord 2004; 42:526–532.

    Article  CAS  PubMed  Google Scholar 

  40. Badía X, Alonso J. Validity and reproducibility of the Spanish Version of the Sickness Impact Profile. J Clin Epidemiol 1996; 49:359–365.

    Article  PubMed  Google Scholar 

  41. Alonso J, Prieto L, Antó JM. La versión española del SF-36 Health Survey (Cuestionario de Salud SF-36): un instrumento para la medida de los resultados clínicos. Med Clin (Barc) 1995; 104:771–776.

    CAS  Google Scholar 

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Correspondence to Safaa A. Mahran MD.

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Mahran, S.A., Abdulrahman, M.A., Janbi, F.S. et al. The health-related quality of life in stroke survivors: clinical, functional, and psychosocial correlate. Egypt Rheumatol Rehabil 42, 188–195 (2015). https://doi.org/10.4103/1110-161X.168198

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