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Egyptian Rheumatology and Rehabilitation
Fig. 4 | Egyptian Rheumatology and Rehabilitation

Fig. 4

From: Efficacy of adipose—derived stromal vascular fraction in treatment of osteoarthritis: an experimental study

Fig. 4

Photomicrograph of section in adult female rat knee joint stained with Safranin O stain. A Healthy group showing regular and smooth articular cartilage (↑) with homogenous intense orange staining of the matrix of the articular cartilage (*) with apparent tidemark line (↑↑) separating the (DZ) from the (CZ). B Group II at 1 month showing irregular surface and erosion of articular cartilage (↑) with marked decrease in orange staining of the matrix of the cartilage (*). Notice duplication of tidemark (↑↑). C Group III at 1 month exhibits relative increased intensity staining of Safranin O stain of the cartilage matrix particularly in the deep zone (*). D Group II at 2 months still show faint staining intensity of cartilage matrix (*). Notice duplication of tidemark (↑↑). E Group III at 2 months revealed increase in intensity of the Safranin O stain of the cartilage matrix both in the superficial and deep zones (*). Notice apparent tidemark line (↑↑) separating the deep cartilage zone from the calcified zone (CZ). (Safranin O stain, X 400)

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