Fig. 1From: Efficacy of adipose—derived stromal vascular fraction in treatment of osteoarthritis: an experimental studyA The histopathological examination of healthy control demonstrated that the surface of the articular cartilage was regular and smooth (▲). The chondrocytes are arranged into 4 zones: Superficial zone (SZ); intermediate zone (IZ); deep zone (DZ); and calcified cartilage zone (CZ). A transverse tidemark (dashed line) can be noticed. B Section of Knee joint showing early degenerative changes in cartilage 2 weeks after induction of arthritis. The surface of the articular cartilage shows fibrillations, irregularity (↑) and areas with shed off apoptotic chondrocytes (arrowhead). The cartilage matrix is pale stained (*). (H&E × 400)Back to article page