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Table 7 Multivariate logistic regression analysis for factors predictors for ILD in scleroderma patients

From: Significance of serum Krebs von den Lungen-6 in systemic sclerosis

  

Wald

Sig.

OR

95% C.I.

Lower

Upper

Age (years)

0.688

3.683

0.031*

1.732

1.235

4.423

Sex

0.247

1.362

0.162

1.682

1.105

2.748

BMI (wt/(ht)^2)

0.368

3.292

0.041*

2.896

1.341

7.696

Disease duration (years)

0.408

0.765

0.961

0.459

0.122

1.137

Esophgeal dysmotility

0.889

0.773

0.611

0.526

0.142

1.211

Raynaud's phenomena

0.289

1.594

0.190

1.968

1.293

3.215

Digital ulceration

0.192

1.293

0.340

1.366

0.974

2.207

Digital gangrene

0.266

1.587

0.294

1.842

1.213

2.893

PAH

1.040

0.904

0.715

0.615

0.166

1.417

MRSS

2.531

2.028

0.049*

1.848

1.452

2.945

ESR (mm/h)

0.349

0.654

0.821

0.392

0.104

0.972

CRP

0.225

1.513

0.398

1.598

1.140

2.582

ANA (IU/ml)

0.177

0.913

0.374

1.362

0.972

2.147

Anti-SCL70 (IU/ml)

0.366

2.547

0.043*

1.943

1.861

3.327

Krebs von den Lungen-6 (U/ml)

1.549

7.353

0.026*

2.822

1.486

5.461

FVC (L)

2.254

8.349

< 0.001**

3.014

1.985

6.068

TLC (L)

0.994

5.736

0.027*

2.712

2.056

6.446

DLCO (L)

0.889

4.710

0.029*

1.740

1.646

4.915

Medsger severity scale

1.272

5.838

0.027*

1.702

1.606

5.177

  1. β regression coefficient, SE standard error, CI confidence interval, OR odds ratiol, PAH pulmonary arterial hypertension, MRSS modified Rodnan skin score, ESR erythrocyte sedimentation rate, CRP C-reactive protein, ANA antinuclear antibodies, Anti-SCl70 anti-Sclerodema 70 antibody, FVC forced vital capacity, TLC total lung capacity, DLCO diffusion lung carbon dioxide capacity