Correlation of hematological parameters, antibodies and cytokines with disease activity in systemic lupus erythematosus: a cross-sectional study

Egyptian Rheumatology and Rehabilitation

Table 3 Correlation of SLEDAI with demographic, clinical, and laboratory parameters

Variables	SLEDAI
Variables	r	p
Age	− 0.305	< 0.001
Disease duration	− 0.145	0.068
Age at disease onset	− 0.196	0.013
ESR	0.542	< 0.001
CRP	0.287	< 0.001
Anti-dsDNA ab	0.407	< 0.001
Anti-nucleosome ab	0.443	< 0.001
Anti-C1q at	0.382	< 0.001
C3	− 0.336	< 0.001
Serum MCP-1	0.318	< 0.001
Urinary MCP-1	0.431	< 0.001
NLR	0.323	< 0.001
PLR	0.303	< 0.001
SDI	0.268	0.006
Physician’s global assessment	0.896	< 0.001

SLEDAI Systemic Lupus Erythematosus Disease Activity Index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, anti-dsDNA Ab anti-double-stranded deoxyribonucleic acid antibodies, ab antibodies, C3 complement component C3, MCP-1 monocyte-chemoattractant protein-1, NLR neutrophil-to-lymphocyte ratios, PLR platelet-to-lymphocyte ratios, SDI Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for SLE, r correlation coefficient
p ≤ 0.05 values were accepted as statistically significant