Table 2 Differences in the age, sex, serum cytokines level, and NFC changes between SLE patients and control group
Parameters | Controls (n = 20) | SLE patients (n = 53) | P value |
|---|---|---|---|
Age (years) | 34.21 ± 11.4 | 32.5 ± 10.6 | NS |
Sex (M/F) | 6/14 | 7/46 | NS |
IL-17A (ng/ml) | 1.23 ± 0.16 | 3.137 ± 0.7 | < 0.0001 |
IFN-α (ng/ml) | 0.185 ± 0.019 | 0.371 ± 0.081 | < 0.0001 |
IFN-β (ng/ml) | 0.173 ± 0.019 | 0.441 ± 0.081 | < 0.0001 |
Capillary density (/mm) | 8.6 ± 1.13 | 7 ± 1.23 | 0.02 |
Capillary length (μm) | 231.1 ± 13.84 | 276.2 ± 43.5 | 0.0073 |
Elongated capillaries (n/%) | 0/0 | 35/66 | < 0.0001 |
Dilated capillaries (n/%) | 0/0 | 13/24.5 | 0.015 |
Giant capillaries (n/%) | 0/0 | 3/5.66 | NS |
Avascular area (n/%) | 0/0 | 4/7.55 | NS |
Branched capillaries (n/%) | 0/0 | 7/13.2 | NS |
Crossed capillaries (n/%) | 0/0 | 18/34 | 0.0017 |
Tortuous capillaries (n/%) | 0/0 | 30/56.6 | < 0.0001 |
Sluggish capillaries (n/%) | 0/0 | 4/7.55 | NS |
Hemorrhages (n/%) | 0/0 | 6/11.32 | NS |