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Table 4 laboratory parameters in different disease activity groups

From: Platelet/lymphocyte, neutrophil/lymphocyte, and lymphocyte/monocyte ratios as biomarkers for rheumatoid arthritis: correlation with disease activity

Item

(Meanā€‰Ā±ā€‰SD)

Remission (21)

Low (13)

Moderate (37)

High (49)

P value

DAS28

2.09ā€‰Ā±ā€‰0.5

3.05ā€‰Ā±ā€‰0.132

4.4ā€‰Ā±ā€‰0.545

5.83ā€‰Ā±ā€‰0.5

P1ā€‰=ā€‰0.111

P2ā€‰<ā€‰0.001

P3ā€‰<ā€‰0.001

ESR

34.57ā€‰Ā±ā€‰11.83

27.38ā€‰Ā±ā€‰11.5

38.4ā€‰Ā±ā€‰11.78

73.16ā€‰Ā±ā€‰23.9

P1ā€‰=ā€‰0.66

P2ā€‰=ā€‰0.22

P3ā€‰<ā€‰0.001

CRP

15.01ā€‰Ā±ā€‰7.23

16.07ā€‰Ā±ā€‰8.73

15.62ā€‰Ā±ā€‰5.49

41.06ā€‰Ā±ā€‰14.48

P1ā€‰=ā€‰0.99

P2ā€‰=ā€‰0.1

P3ā€‰<ā€‰0.001

Hemoglobin

12.01ā€‰Ā±ā€‰1.27

11.96ā€‰Ā±ā€‰1.37

11.59ā€‰Ā±ā€‰1.5

11.16ā€‰Ā±ā€‰1.46

P1ā€‰=ā€‰0.1

P2ā€‰=ā€‰0.86

P3ā€‰=ā€‰0.52

Platelets

238.8ā€‰Ā±ā€‰18.51

265.53ā€‰Ā±ā€‰39.04

281.44ā€‰Ā±ā€‰38.54

285.38ā€‰Ā±ā€‰40.56

P1ā€‰=ā€‰0.11

P2ā€‰=ā€‰0. 66

P3ā€‰=ā€‰0.97

WBCs

7.13ā€‰Ā±ā€‰2.31

5.93ā€‰Ā±ā€‰1.42

6.89ā€‰Ā±ā€‰1.72

7.7ā€‰Ā±ā€‰2.82

P1ā€‰=ā€‰0.46

P2ā€‰=ā€‰0. 57

P3ā€‰=ā€‰0.38

Lymphocytes

2.23ā€‰Ā±ā€‰0.26

1.97ā€‰Ā±ā€‰0.22

1.72ā€‰Ā±ā€‰0.31

1.56ā€‰Ā±ā€‰0.24

P1ā€‰=ā€‰0. 041

P2ā€‰=ā€‰0.023

P3ā€‰=ā€‰0.04

Neutrophils

2.87ā€‰Ā±ā€‰0.68

3.38ā€‰Ā±ā€‰0.29

3.83ā€‰Ā±ā€‰0.17

4.21ā€‰Ā±ā€‰0.618

P1ā€‰=ā€‰0. 028

P2ā€‰=ā€‰0.032

P3ā€‰=ā€‰0.005

Monocytes

0.034Ā±0.035

0.4ā€‰Ā±ā€‰0.03

0.49ā€‰Ā±ā€‰0.08

0.58ā€‰Ā±ā€‰0.09

P1ā€‰=ā€‰0. 24

P2ā€‰=ā€‰0.002

P3ā€‰<ā€‰0.001

PLR

94.95ā€‰Ā±ā€‰17.07

129.52ā€‰Ā±ā€‰38.22

162.32ā€‰Ā±ā€‰41.56

187.19ā€‰Ā±ā€‰39.8

P1ā€‰=ā€‰0. 048

P2ā€‰=ā€‰0.045

P3ā€‰=ā€‰0.019

NLR

1.13ā€‰Ā±ā€‰0.26

1.66ā€‰Ā±ā€‰0.5

2.21ā€‰Ā±ā€‰0.48

2.77ā€‰Ā±ā€‰0.64

P1ā€‰=ā€‰0. 028

P2ā€‰=ā€‰0.009

P3ā€‰<ā€‰0.001

LMR

6.39ā€‰Ā±ā€‰0.85

4.94ā€‰Ā±ā€‰0.718

3.58ā€‰Ā±ā€‰0.86

2.71ā€‰Ā±ā€‰0.61

P1ā€‰<ā€‰0.001

P2ā€‰<ā€‰0.001

P3ā€‰<ā€‰0.001

  1. Where: PLR is platelet/lymphocyte ratio, NLR is neutrophil/lymphocyte ratio, and LMR is lymphocyte/monocyte ratio. P1 is the significance by comparing the remission with the low disease activity, p2 is the significance by comparing the low disease activity with the moderate disease activity, and p3 is the significance by comparing the moderate disease activity with the high disease activity