Functional ability in knee osteoarthritis: role of neuropathic pain and central sensitization

Egyptian Rheumatology and Rehabilitation

Table 3 Correlation between demographic and clinical data with different measurement (n = 68)

	Age (/years)		Symptoms duration (/years)		Body mass index (kg/m²)		KL
	r_s	p	r_s	p	r_s	p	r_s	p
VAS	-0.200	0.103	0.108	0.379	0.167	0.173	0.173	0.159
PPT right knee	0.015	0.900	0.223	0.067	-0.239	0.050	0.001	0.995
PPT left knee	-0.043	0.726	-0.044	0.724	-0.330^*	0.006^*	-0.457^*	< 0.001^*
PPT right Elbow	-0.120	0.328	-0.076	0.540	-0.372^*	0.002^*	-0.248^*	0.041^*
CSI	0.136	0.270	-0.046	0.711	0.169	0.168	0.228	0.062
PainDetect	0.306^*	0.011^*	0.141	0.251	0.227	0.062	0.542^*	< 0.001^*
DN4	0.271^*	0.026^*	0.165	0.177	0.112	0.365	0.386^*	0.001^*
HAD-D	0.269^*	0.027^*	-0.064	0.604	0.005	0.968	0.210	0.086
HAD-A	0.336^*	0.005^*	-0.050	0.685	-0.131	0.288	0.341^*	0.004^*
Timed up and go	0.398^*	0.001^*	0.095	0.442	0.242^*	0.046^*	0.457^*	< 0.001^*
CST	0.135	0.274	0.099	0.423	-0.138	0.261	-0.042	0.736
KOOS	-0.151	0.218	-0.209	0.088	-0.133	0.279	-0.340^*	0.005^*
KOOS symptoms	-0.212	0.082	-0.076	0.540	-0.383^*	0.001^*	-0.413^*	< 0.001^*
KOOS Pain	0.102	0.410	-0.221	0.070	0.108	0.379	0.019	0.881
KOOS ADL	-0.097	0.429	-0.057	0.644	-0.322^*	0.007^*	-0.413^*	< 0.001^*
KOOS Sports	0.070	0.569	-0.130	0.289	0.261^*	0.032^*	0.212	0.082
KOOS QOL	-0.154	0.209	-0.126	0.306	-0.112	0.365	-0.405^*	0.001^*

r_s: Spearman coefficient
KL Kellgren-Lawrence grading, VAS Visual Analogue Scale, PPT pressure pain threshold, CST performance-based chair and stand test, DN4 Douleur neuropathique 4, HAD-A Hospital Anxiety score, HAD-D Hospital Depression score, CSI central sensitization inventory, KOOS Knee Injury and Osteoarthritis Outcome Score, ADL activity of daily living, QOL quality of life
^*Statistically significant at p ≤ 0.05