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Table 2 Comparison of data with and without RLS in patients with PSS

From: The relationship of the prevalence and severity of restless legs syndrome in primary Sjögren syndrome with insomnia status, anxiety, depression, and neuropathic pain

 

PSS with RLS (12 patient)

PSS without RLS (33 patient)

p value

Age (years)

52.08 ± 11.05

51 (33–71)

46.06±10.16

45 (29–71)

0.093

Gender (female/male)

12 F

31 F/2 M

0.771

Disease duration

3.67 ± 1.37

4 (1–5)

3.42 ± 1.48

4 (0–6)

0.623

Pain threshold right

8.34 ± 2.68

8.25 (4–13)

9.64 ± 3.73

9 (3–18)

0.278

Pain threshold left

8.38 ± 3.27

8 (4–15)

9.30 ± 3.93

10 (2–19)

0.470

Number of painful body sizes

5.17 ± 2.03

5.50 (1–7)

3.64 ± 2.70

3 (0–9)

0.066

FMS

5 FMS + 41.6%

7 FMS–%58.4

7 FMS + 21.21%

26 FMS–78.79%

0.060

BDI

15.17 ± 10.97

12.50 (1–42)

8.21 ± 6.91

6 (1–28)

0.016

BDA

14.50 ± 8.39

13 (4–31)

10.15 ± 8.43

8 (1–36)

0.009

Lower extremity VAS

5 (0–8)

4.50 ± 2.15

4 (0–7)

2.81 ± 2.32

0.034

PDQ

12.17 ± 5.55

12 (2–21)

6.09 ± 6.75

4 (0–23)

0.005

ISI

10 ± 4.88

9.50 (2–17)

8.42 ± 6.05

8 (1–23)

0.015

ESSDAI

4.08 ± 1.56

4 (2–7)

3.85 ± 1.97

4 (0–9)

0.712

ESSPRI

Mean

7.48 ± 0.71

7.50 (6–8.5)

6.24 ± 1.95

6.50 (1.5–9)

0.055

Dryness

7.25 ± 1.48

7.50 (5–9)

5.85 ± 2.58

7 (0–9)

0.124

Fatigue

7.58 ± 1.56

8 (3–9)

6.73 ± 2.26

7 (1–9)

0.424

Pain

7.58 ± 0.99

8 (5–9)

5.91 ± 2.28

6 (1–9)

0.021

  1. PSS primary Sjögren’s syndrome, RLS restless leg syndrome, FMS fibromyalgia syndrome, ISI Insomnia Severity Index, BDI Beck Depression Inventory, BAI Beck Anxiety Inventory, VAS visual analog scale, PDQ Pain Detect Questionnaire, ESSDAI EULAR Sjögren’s Syndrome Disease Activity Index, ESSPRI EULAR Sjögren’s Syndrome Patient Reported Index