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Table 1 Demographic and disease-related characteristics of patients with primary Sjögren’s syndrome and demographic data of healthy controls

From: The relationship of the prevalence and severity of restless legs syndrome in primary Sjögren syndrome with insomnia status, anxiety, depression, and neuropathic pain

 

PSS (n = 45)

Control group (n = 54)

p value

Age (years)

47.67 ± 10.62

45 (29–71)

50.22 ± 8.67

52.50 (32–72)

0.149

Gender (female/male)

43 F (95.6%)/2 M (4.4%)

52 F (%96)/2 M (4%)

0.853

BMI (kg/m2)

   

RLS

12 (26.7%)

33 (73.3%)

5 (%9)

49 (%91)

0.022

RLS severity

1 patient mild RLS

6 patient moderate RLS

4 patient severe RLS

1 patient very severe RLS

1 patient mild RLS

3 patient moderate RLS

1 patient severe RLS

0.037

FMS

13 kişi FMS + 28.9%

32 kişi FMS-71.1%

5 kişi FMS + 9.3%

49 kişi FMS-90.7%

0.012

ISI

9.64 ± 6.06

8 (1–23)

6.44 ± 4.30

6 (1–23)

0.007

BDI

10.44 ± 8.15

9 (1–36)

7.61 ± 5.16

6 (0–23)

0.047

BAI

10.22 ± 7.84

10 (0–36)

7.28 ± 5.01

5 (0–24)

0.033

Lower extremity VAS

4 (0–8)

0 (0–8)

0.001

PDQ

7.71 ± 6.94

6 (0–23)

5.04 ± 4.17

5 (0–20)

0.099

Pain threshold right

9.29 ± 3.50

9 (3–18)

8.92 ± 3.57

9 (3–17)

0,816

Pain threshold left

9.06 ± 3.75

9 (2–19)

9.50 ± 3.19

10 (3–15)

0,370

Number of painful body sizes

4.04 ± 2.61

4 (0–9)

2 ± 1.94

1 (0–7)

< 0.001

ESSDAI

3.91 ± 1.85

4 (0–9)

  

ESSPRI

Mean

6.57 ± 1.79

7 (1.5–9)

  

Dryness

6.22 ± 2.41

7 (0–9)

  

Fatigue

6.96 ± 2.12

8 (1–9)

  

Pain

6.36 ± 2.06

7 (1–9)

  

Disease duration

3.49 ± 1.44

4 (1–6)

  
  1. PSS primary Sjögren’s syndrome, BMI body mass index, RLS restless leg syndrome, FMS fibromyalgia syndrome, ISI Insomnia Severity Index, BDI Beck Depression Inventory, BAI Beck Anxiety Inventory, VAS visual analog scale, PDQ Pain Detect Questionnaire, ESSDAI EULAR Sjögren’s Syndrome Disease Activity Index, ESSPRI EULAR Sjögren’s Syndrome Patient Reported Index