Skip to main content

Table 1 Multiple linear and logistic regression analysis of LORA

From: Efficacy and gastrointestinal tolerability of methotrexate in late-onset rheumatoid arthritis patients: a prospective cohort study

Variable

Gender

Seropositive RA

Erosive RA

MTX nonresponder

MTX withdrawal due to adverse event

Large joint involvement

p: 0.350

OR: 0.707

p: 0.237

OR: 0.609

p: 0.315

OR: 1.513

p: 0.193

OR: 0.389

p: 0.368

OR: 1.929

Only large joint involvement

p: 0.629

OR: 0.930

p: 0.594

OR: 1.231

p: 0.435

OR: 0.463

p: 0.463

OR: 1.109

p: 0.109

OR: 5.80

Extraarticular manifestations

p: 0.136

OR: 0.894

p: 0.371

OR: 2.56

p: 0.453

OR: 1.704

p: 0.471

OR: 2.036

p: 0.077

OR: 7.86

MTX nonresponders

p: 0.203

OR: 3.675

p: 0.654

OR: 1.009

p: 0.577

OR: 0.796

NA

p: 0.030

OR: 8.55

MTX withdrawal due to adverse events

p: 0.606

OR: 1.190

p: 0.236

OR: 0.413

p: 0.339

OR: 0.377

p: 0.030

OR: 8.55

NA

Symptom duration

p: 0.653

β: −0.063

p: 0.470

β: −0.100

p: 0.085

β: −0.218

p: 0.323

β: 0.131

p: 0.991

β: −0.002

Age

p: 0.844

β: 0.028

p: 0.065

β: 0.259

p: 0.026*

β: −0.284

p: 0.592

β: −0.071

p: 0.968

β: 0.006

DAS28

p: 0.627

β: 0.489

p: 0.753

β: 0.126

p:0.881

β: −0.054

p: 0.381

β: −0.335

p: 0.781

β: 0.114

SDAI

p: 0.869

β: 0.180

p: 0.728

β: 0.373

p: 0.032*

β: 2.12

p: 0.949

β: −0.066

p: 0.361

β: −1.008

CDAI

p: 0.763

β: −0.023

p: 0.690

β: −0.348

p: 0.041*

β: −1.64

p: 0.892

β: −0.113

p: 0.449

β: 0.681

CRP

p: 0.986

β: 0.009

p: 0.630

β: −0.248

p: 0.048*

β: −0.933

p: 0.476

β: 0.350

p: 0.481

β: 0.373

  1. LORA late-onet rheumatoid arthritis, RA rheumatoid arthritis, MTX methotrexate, DAS28 disease activity score-28, SDAI simple disease activity index, CDAI clinical disease activity index, CRP C-reactive protein, OR odds ratio, NA not applicable.
  2. *Means significance (p ≤ 0.05 is statistically significant)