Table 4 Association of IL16 level, WOMAC, and K/L score with IL16 genotypes
From: Genetic polymorphisms of interleukin-16 in Egyptian patients with primary knee osteoarthritis
Genotypes | Variables | ||||||
|---|---|---|---|---|---|---|---|
IL16 | WOMAC | Kellgren | |||||
Median | Range | Median | Range | Median | Range | ||
rs11556218 | TT (N = 90) | 210.8 | 55.3–484.5 | 71 | 53–96 | 3 | 2–4 |
TG (N = 48) | 155.9 | 23.7–418.4 | 44 | 30–53 | 2 | 1–2 | |
GG (N = 12) | 274 | 55.7–460.4 | 25 | 8–30 | 1 | 1–1 | |
TG + GG (N = 60) | 155.9 | 23.7–460.4 | 43 | 8–53 | 2 | 1–2 | |
P1 | 0.328 | * < 0.001 | * < 0.001 | ||||
P2 | 0.338 | * < 0.001 | * < 0.001 | ||||
rs4778889 | TT (N = 101) | 207 | 23.7–484.5 | 69 | 8–96 | 2.5 | 11–4 |
TC (N = 44) | 189.1 | 29.6–424.4 | 43 | 22–56 | 2 | 1–2 | |
CC (N = 5) | 291.9 | 96.9–460.4 | 21 | 8–53 | 1 | 1–2 | |
TC + CC (N = 49) | 194 | 29.6–460.4 | 43 | 8–56 | 2 | 1–2 | |
P3 | 0.593 | * < 0.001 | * < 0.001 | ||||
P4 | 0.890 | * < 0.001 | * < 0.001 | ||||
rs4072111 | CC(N = 110) | 203.7 | 23.7–484.5 | 67.5 | 29–96 | 2.5 | 1–4 |
CT(N = 36) | 227.1 | 29.6–424.4 | 36.5 | 19–56 | 2 | 1–2 | |
TT(N = 4) | 123.9 | 96.9–150.8 | 30.5 | 8–53 | 1.5 | 1–2 | |
CT + TT(N = 40) | 155.9 | 29.6–424.4 | 36.5 | 8–56 | 2 | 1–2 | |
P5 | 0.298 | * < 0.001 | * < 0.001 | ||||
P6 | 0.971 | * < 0.001 | * < 0.001 | ||||