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Egyptian Rheumatology and Rehabilitation

Table 3 Analysis of rs11556218, rs4778889, and rs4072111 haplotypes in OA cases and controls

From: Genetic polymorphisms of interleukin-16 in Egyptian patients with primary knee osteoarthritis

Haplotype

rs11556218

rs4778889

rs4072111

Control

Cases

p

OR

95% CI

TTC

T

T

C

0.401

0.688

-

1

(reference)

GTC

G

T

C

0.267

0.092

* < 0.001

0.282

0.177–0.449

TCT

T

C

T

0.155

0.044

* < 0.001

0.250

0.132–0.474

GCT

G

C

T

0.047

0.062

0.398

1.381

0.679–2.809

GCC

G

C

C

0.046

0.058

0.519

1.227

0.594–2.537

GTT

G

T

T

0.037

0.028

0.558

0.810

0.331–1.983

TCC

T

C

C

0.043

0.016

*0.051

0.374

0.132–1.063

  1. OR Odds ratio, CI Confidence interval
  2. *Significance P ≤ 0.05
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