Table 2 Comparison of IL16 SNPs between OA patients and controls
From: Genetic polymorphisms of interleukin-16 in Egyptian patients with primary knee osteoarthritis
Genotype | Groups | |||||||
|---|---|---|---|---|---|---|---|---|
Control N = 150 | Cases N = 150 | P | OR | 95% CI | ||||
N | % | N | % | |||||
rs11556218 | TT | 49 | 32.7 | 90 | 60.0 | - | 1 | (reference) |
TG | 83 | 55.3 | 48 | 32.0 | * < 0.001 | 0.315 | 0.191–0.518 | |
GG | 18 | 12.0 | 12 | 8.0 | *0.014 | 0.363 | 0.162–0.815 | |
TG + GG | 101 | 67.3 | 60 | 40.0 | * < 0.001 | 0.323 | 0.202–0.519 | |
T | 181 | 60.3 | 228 | 76.0 | - | 1 | (reference) | |
G | 119 | 39.7 | 72 | 24.0 | * < 0.001 | 0.480 | 0.338–0.683 | |
HW p | 0.056 | 0.133 | ||||||
rs4778889 | TT | 75 | 50.0 | 101 | 67.3 | - | 1 | (reference) |
CT | 63 | 42.0 | 44 | 29.3 | *0.008 | 0.519 | 0.319–0.844 | |
CC | 12 | 8.0 | 5 | 3.3 | *0.034 | 0.309 | 0.105–0.916 | |
TC + CC | 75 | 50.0 | 49 | 32.7 | *0.002 | 0.485 | 0.304–0.775 | |
T | 213 | 71.0 | 246 | 82.0 | - | 1 | (reference) | |
C | 87 | 29.0 | 54 | 18.0 | *0.001 | 0.537 | 0.365–0.791 | |
HW p | 0.807 | 0.938 | ||||||
rs4072111 | CC | 87 | 58.0 | 110 | 73.3 | - | 1 | (reference) |
CT | 53 | 35.3 | 36 | 24.0 | *0.017 | 0.537 | 0.323–0.893 | |
TT | 10 | 6.7 | 4 | 2.7 | *0.049 | 0.316 | 0.096–0.843 | |
CT + TT | 63 | 42.0 | 40 | 26.7 | *0.005 | 0.502 | 0.309–0.816 | |
C | 227 | 75.7 | 256 | 85.3 | - | 1 | (reference) | |
T | 73 | 24.3 | 44 | 14.7 | *0.004 | 0.534 | 0.353–0.809 | |
HW p | 0.619 | 0.614 | ||||||