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Table 1 Demographic and clinical characteristics data of the patients (n = 100)

From: Bone mineral density changes in osteoporotic and osteopenic patients after COVID-19 infection

 

Total (n = 100)

COVID (n = 56)

Non-COVID (n = 44)

Test of Sig

p

Age (years)

 Mean ± SD

62.31 ± 7.88

62.84 ± 9.05

61.64 ± 6.10

t = 0.792

0.431

Sex

 Male

26 (26.0%)

15 (26.8%)

11 (25.0%)

χ2 = 0.041

0.840

 Female

74 (74.0%)

41 (73.2%)

33 (75.0%)

BMI (kg/m2)

 Mean ± SD

28.48 ± 5.75

28.34 ± 6.03

28.67 ± 5.44

t = 0.283

0.778

Total physical activity

 Inactive

62 (62.0%)

36 (64.3%)

26 (59.1%)

χ2 = 0.282

0.595

 Moderately active

38 (38.0%)

20 (35.7%)

18 (40.9%)

 Active

0 (0.0%)

0 (0.0%)

0 (0.0%)

Smoking

30 (30.0%)

15 (26.8%)

15 (34.1%)

χ2 = 0.626

0.429

Comorbidity

 No comorbidity

18 (18.0%)

8 (14.3%)

10 (22.7%)

χ2 = 2.575

0.63

 Rheumatologic disease

43 (43.0%)

24 (42.8%)

19 (43.2%)

 Cardiac

32 (32.0%)

17 (30.4%)

15 (34.1%)

 HTN

60 (60.0%)

36 (64.3%)

24 (54.5%)

 DM

50 (50.0%)

32 (57.1%)

18 (40.9%)

Osteoporosis vs. osteopenia

 Osteopenia

60 (60.0%)

38 (67.9%)

22 (50.0%)

χ2 = 3.274

0.070

 Osteoporosis

40 (40.0%)

18 (32.1%)

22 (50.0%)

Osteoporosis duration (years)

 Median (min.–max.)

4 (2–7)

4 (2–6)

4 (2–7)

U = 1134.0

0.483

Compression fracture

21 (21.0%)

12 (21.4%)

9 (20.5%)

χ2 = 0.014

0.906

Treatment received

Denosumab

56 (56.0%)

29 (51.79%)

27 (61.36%)

χ2 = 0.92

0.34

Bisphosphonate

26 (26.0%)

16 (28.57%)

10 (22.72%)

χ2 = 1.59

0.21

Teriparatide

18 (18.0%)

11 (19.64%)

7 (15.92%)

χ2 = 0.232

0.63

Ca/vitamin D

98 (98.0%)

56 (100.0%)

42 (95.5%)

χ2 = 2.597

FEp = 0.191

Corticosteroid use

43 (43.0%)

24 (51.8%)

19 (31.8%)

χ2 = 0.001

0. 97

Duration of corticosteroid (years)

 Median (min–max)

0 (0–6)

2 (0–6)

0 (0–6)

U = 975.5

0. 075

Hospitalization

 Hospital admission

40 (40.0%)

40 (71.4%)

 Days of admission

  Mean ± SD

(n = 40)

(n = 40)

(n = 0)

  

8.83 ± 4.13

8.83 ± 4.13

  1. SD standard deviation, U Mann–Whitney test, t Student t-test, χ2 chi square test, BMI body mass index, HTN hypertension, DM diabetes mellitus, Ca calcium, COVID coronavirus disease, p,p value for comparing between COVID and non-COVID
  2. *Statistically significant at p ≤ 0.05