From: Predictors of relapse in granulomatosis with polyangiitis: a multi-center study
 | Relapsing group (n = 147) | Non-relapsing group (n = 107) | P |
---|---|---|---|
Age (years) | 43.8 ± 16.6 | 45.6 ± 15.1 | 0.31 |
Gender (female) | 77 (52.4%) | 45 (42.1%) | 0.07 |
Initial presentation: ear | 53 ( 36.1%) | 42 ( 39.3%) | 0.34 |
Initial presentation: nose | 36 (24.5%) | 39 (36.4%) | 0.03 |
Initial presentation: sinus | 36 (24.5%) | 36 (33.6%) | 0.07 |
Initial presentation: eye | 12 (8.2%) | 5 (4.7%) | 0.20 |
Initial presentation: lung | 14 ( 9.5%) | 2 (1.9%) | 0.01 |
Initial presentation: kidney | 0 | 1 (0.9%) | 0.42 |
Initial presentation: skin | 2 (1.4%) | 0 | 0.33 |
Initial presentation: arthritis | 0 | 1 (0.9%) | 0.42 |
Initial presentation: brain vascular | 90 (61.2%) | 72 (67.3%) | 0.19 |
Initial presentation: subglot | 7 (4.8%) | 4 (3.7%) | 0.47 |
pseudotumor | 32 (21.8%) | 30 (28.0%) | 0.15 |
Positive PR3-ANCA | 108 (73.5%) | 55 (51.4) |  < 0.001 |
Positive MPO-ANCA | 12 ( 8.2%) | 24 (22.4%) | 0.001 |
eosinophilia | 3 (2.0%) | 7 (6.5%) | 0.07 |
BVAS at diagnosis | 17.4 ± 7.9 | 13.6 ± 6.7 |  < 0.001 |
BVAS at diagnosis ≥ 8.5 | 130 (88.4%) | 17 (11.6%) | 0.01 |
During follow-up: nose | 115 ( 78.2%) | 73 (68.2%) | 0.05 |
During follow-up: sinus | 140 (95.2%) | 98 (91.6%) | 0.18 |
During follow-up: glottal | 25 (17.0%) | 14 (13.1%) | 0.25 |
During follow-up: ear | 101 (68.7%) | 70 (65.4%) | 0.34 |
During follow-up: lung | 113 (76.9%) | 82 (76.6%) | 0.54 |
During follow-up: kidney | 65 (44.2%) | 52 (48.6%) | 0.29 |
During follow-up: eye | 53 (36.1%) | 29 (27.1%) | 0.08 |
During follow-up: CNS | 46 (31.3%) | 35 (32.7%) | 0.46 |
During follow-up: mucosal membranes | 29 (19.7%) | 6 (5.6%) | 0.001 |
During follow-up: skin | 22 (15.0%) | 8 (7.5%) | 0.05 |
During follow-up: heart | 9 (6.1%) | 1 (0.9%) | 0.03 |
During follow-up: GI | 17 (11.6%) | 2 (1.9%) | 0.002 |
During follow-up: arthritis | 16 (10.9%) | 3 (2.8%) | 0.01 |