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Table 2 Laboratory results and medications received by patients suffering from psoriasis-related enthesitis and those without enthesitis

From: Burden of enthesitis on the quality of life and work productivity in psoriatic arthritis patients

Variables

Total PSA (n = 88)

Patients with enthesitis (n = 44)

Patients without enthesitis (n = 44)

Test

p-value

DAPSA

 (mean ± SD)

16.17 ± 6.91

19.82 ± 6.17

12.52 ± 5.59

−4.979

< 0.001*

 Median (IQR)

16 (12–22)

20 (16–24)

12 (10–16)

  

PASI

 (mean ± SD)

12.74 ± 10.22

13.82 ± 10.28

11.66 ± 10.15

−1.914

0.056

 Median (IQR)

10 (6–16)

10 (8–16)

8 (5–14)

  

PSAID 12

   

−8.228

< 0.001*

 (mean ± SD)

4.63 ± 3.42

7.79 ± 1.69

1.45 ± 0.5

  

 Median (IQR)

3.5 (1–8)

8 (6–9)

1 (1–2)

SPARCC index

   

−8.686

< 0.001*

 (mean ± SD)

3.73 ± 3.99

7.45 ± 1.93

0

  

 Median (IQR)

1.5 (0–8)

8 (6–8)

 

Acute phase reactant

ESR

30.05 ± 7.96

29.36 ± 6.22

30.73 ± 9.42

−0.802

0.425

CRP

   

−1.852

0.064

Median (IQR)

8.72 ± 12.17

5.2 (3.9–8.2)

11.37 ± 16.35

7.6 (4.2–8.2)

6.07 ± 4.23

5.2 (2.8–7.6)

  

NSJ

2.6 ± 1.08

2.43 ± 0.87

2.79 ± 1.2

−1.58

0.117

NTJ

13.92 ± 4.3

14.54 ± 4.12

13.29 ± 4.61

1.33

0.184

Current medications, n (%)

NSAIDs

70 (79.5%)

44 (100%)

26 (59.1%)

22.629

< 0.001*

Corticosteroids

6 (6.8%)

4 (9.1%)

2 (4.5%)

0.715

0.398

c-DMARDs

MTX

18 (20.5%)

7 (15.9%)

11 (25%)

1.117

0.290

SSZ

3 (3.4%)

3 (6.8%)

0

3.106

0.078

Biological

Anti-TNF

25 (28.4%)

14 (31.8%)

11 (25%)

0.503

0.478

Anti-IL-17

40 (45.5%)

23 (52.3%)

17 (38.6%)

1.650

0.199

  1. DAPSA disease activity in psoriatic arthritis disease, PASI Psoriasis Area and Severity Index, PSAID psoriatic arthritis impact of disease, SPARCC index Spondyloarthritis Research Consortium of Canada index, ESR erythrocyte sedimentation rate, CRP C-reactive protein, NSJ number of swollen joints, NTJ number of tender joints, NSAIDs nonsteroidal anti-inflammatory drugs, c-DMARDs conventional disease-modifying antirheumatic drugs, MTX methotrexate, SSZ salazopyrine, anti-TNF anti-tumor necrosis factors, anti-IL-17 anti-interleukin-17, *P ≤ 0.05 = significant