Table 2 List of medication and their advised doses which are recommended for induction therapy (class III/IV) lupus nephritis
Medication | Advised dose |
|---|---|
Cyclophosphamide | High dose: Monthly boluses of 0.5–1.0 g/m2 IV × 6 months Low dose (Euro-Lupus protocol): 500 mg IV every 2 weeks × 6 doses |
Rituximab | 1000 mg on days 0 and 14 |
Cyclosporine | 50–200 mg/day |
Mycophenolate mofetil (MMF) | 2–3 g/day, reduced dose: 1 to 2 g/day [use MMF or mycophenolic acid in equivalent dose] |
Tacrolimus | 0.1 mg/kg/day |
Voclosporine | 23.7 mg oral, twice daily |