Table 3 Correlation between basic characteristics of participants and post-vaccination adverse events
Post-vaccination adverse events | Age Mean (SD) | Gender % | Associated comorbidity % | Previous COVID infection % | Disease duration Mean (SD) | JADAS-10 before vaccination Mean (SD) |
|---|---|---|---|---|---|---|
Local AE (at least one AE) | Yes 13.8 (3.0) No 12.3 (3.0) P = 0.3 | F 70.8 M 58.3 P = 0.5 | Yes 62.5 No 67.9 P = 1 | Yes 60 No 67.1 P = 1 | Yes 4.4 (2.6) No 4.7 (2.7) P = 1 | Yes 1.3 (1.3) No 1.6 (1.7) P = 0.6 |
Pain at site of injection | Yes 13.6 (3.1) No 12.8 (3.0) P = 0.6 | F 62.5 M 58.3 P = 1 | Yes 62.5 No 60.7 P = 1 | Yes 40 No 64.5 P = 0.4 | Yes 4.3 (2.7) No 4.9 (2.5) P = 0.6 | Yes 1.4 (1.4) No 1.5 (1.6) P = 0.9 |
Swelling | Yes 12.7 (3.8) No 13.5 (2.9) P = 0.8 | F 20.8 M 25 P = 1 | Yes 37.5 No 17.9 P = 0.3 | Yes 0 No 25.8 P = 0.6 | Yes 4.1 (2.6) No 4.6 (2.6) P = 0.7 | Yes 1.3 (1.1) No 1.5 (1.5) P = 0.9 |
Erythema | Yes 13.8(3.4) No 13.1 (3) P = 0.5 | F 25 M 25 P = 1 | Yes 50 No 17.9 P = 0.1 | Yes 0 No 29 P = 0.3 | Yes 4.2 (2.6) No 4.6 (2.6) P = 0.8 | Yes 1.7 (1.3) No 1.3 (1.5) P = 0.4 |
Ipsilateral painful LNs | Yes ( −) ( −) No 13.3 (3.1) P = − | F 0 M 0 P = − | Yes 0.0 No 0.0 P = − | Yes 0 No 0 P = − | Yes ( −) ( −) No 4.5 (2.6) P = ( −) | Yes ( −) ( −) No 1.4 (1.5) P = ( −) |
Systemic AE (at least one AE) | Yes 13.6 (3.0) No 12.8 (3.2) P = 0.4 | F 66.7 M 50 P = 0.5 | Yes 62.5 No 60.7 P = 1 | Yes 80 No 58 P = 0.6 | Yes 4.3 (2.7) No 4.8 (2.4) P = 0.5 | Yes 1.7 (1.5) No 1 (1.3) P = 0.2 |
Fever | Yes 14.2 (1.7) No 12.8 (3.3) P = 0.07 | F 25 M 25 P = 1 | Yes 25 No 25 P = 1 | Yes 20 No 25.8 P = 1 | Yes 4.4 (2.9) No 4.5 (2.5) P = 0.7 | Yes 1.9 (1.5) No 1.3 (1.4) P = 0.2 |
Chills | Yes 11.6 (3.2) No 13.5 (3.0) P = 0.4 | F 4.2 M 25 P = 0.1 | Yes 12.5 No 10.7 P = 1 | Yes 0 No 12.9 P = 1 | Yes 4 (0.8) No 4.6 (2.7) P = 0.6 | Yes 1.4 (1.1) No 1.4 (1.5) P = 0.9 |
Headache | Yes 14.2 (2.9) No 12.6 (3.1) P = 0.1 | F 54.2 M 25 P = 0.1 | Yes 37.5 No 36.4 P = 0.7 | Yes 80 No 38.7 P = 0.1 | Yes 4.9 (2.8) No 4.2 (2.4) P = 0.4 | Yes 1.5 (1.6) No 1.4 (1.4) P = 0.7 |
Diarrhea | P = − | P = − | P = − | P = − | P = − | P = − |
Nausea | Yes 15.2 (1) No 12.8 (3.2) P = 0.03 | F 25 M 8.3 P = 0.4 | Yes 25 No 17.9 P = 0.6 | Yes 40 No 16.1 P = 0.2 | Yes 3.9 (1.9) No 4.7 (2.7) P = 0.5 | Yes 1.5 (1.6) No 1.4 (1.5) P = 0.8 |
Myalgia | Yes 13.3 (2.6) No 13.2 (3.4) P = 1 | F 37.5 M 50 P = 0.5 | Yes 25 No 44.4 P = 0.4 | Yes 80 No 35.5 P = 0.1 | Yes 3.5 (2.2) No 5.2 (2.3) P = 0.06 | Yes 1.9 (1.6) No1.1 (1.3) P = 0.2 |
Tiredness | Yes 13.6 (2.8) No 13.1 (3.3) P = 0.7 | F 45.8 M 33.3 P = 0.5 | Yes 50 No 58.3 P = 0.7 | Yes 60 No 38.7 P = 0.6 | Yes 4.6 (2.9) No 4.5 (2.4) P = 0.9 | Yes 1.3 (1.2) No 1.5 (1.6) P = 1 |
New transient joint pain | Yes 10.3 (3.1) No 13.6 (3.0) P = 0.1 | F 4.2 M 16.7 P = 0.3 | Yes 12.5 No 5.6 P = 0.5 | Yes 0 No 9.7 P = 1 | Yes 3 (2) No 4.6 (2.6) P = 0.3 | Yes 2 (1.0) No 1.4 (1.5) P = 0.3 |
Allergy | Yes 12.5 ( −) No 13.3 (3.1) P = 0.7 | F 0 M 8.3 P = 0.3 | Yes 0.0 No11.1 P = 1 | Yes 0 No 3.2 P = 1 | Yes 4 ( −) No 4.5 (2.6) P = 0.8 | Yes 2.5 ( −) No 1.4 (1.5) P = 0.6 |
Flaring of 1ry disease | Yes 7 ( −) No 13.5 (3) P = 0.1 | F 4.2 M 0 P = 1 | P = − | Yes 0 No 3.2 P = 1 | Yes 5 ( −) No 4.5 (2.6) P = 0.8 | Yes 1 ( −) No 1.4 (1.5) P = 1 |
Chest pain | Yes 11.5 (6.4) No 13.4 (2.9) P = 0.7 | F 8.3 M 0 P = 0.5 | Yes 0.0 No 8.3 P = 1 | Yes 0.0 No 6.5 P = 1 | Yes 5 (0.0) No 4.5 (2.7) P = 0.6 | Yes 0.5 (0.7) No 1.5 (1.5) P = 0.5 |
Serious AE | P = − | P = − | P = − | P = − | P = − | P = − |