Table 2 Laboratory characteristics of SLE patients at conception according to the occurrence of adverse outcomes
From: Risk assessment score for adverse pregnancy outcome in systemic lupus erythematosus patients
Variable | All SLE patients (n = 116) | With adverse outcomes n = 62 (53.4%) | Without adverse outcomes n = 54 (46.6%) | Test | P | |||
|---|---|---|---|---|---|---|---|---|
no. | % | no. | % | no. | % | |||
Anemia | 73 | 62.9 | 43 | 69.4 | 30 | 55.6 | 2.356 | 0.125c |
Leucopenia | 19 | 16.37 | 11 | 17.74 | 8 | 14.81 | 0.18 | 0.67c |
Thrombocytopenia | 10 | 8.62 | 6 | 9.67 | 4 | 7.4 | f | 0.74d |
Antinuclear antibody | 113 | 97.41 | 61 | 98.38 | 52 | 96.29 | f | 0.59 d |
Hypocomplementemia C3 | 47 | 40.51 | 42 | 67.74 | 5 | 9.3 | 54.03 | .000c* |
Hypocomplementemia C4 | 41 | 35.34 | 28 | 45.2 | 13 | 24.1 | 5.6 | 0.017c* |
Anti-ds DNA antibody | 30 | 25.9 | 23 | 37.1 | 7 | 12.96 | 8.767 | .003c* |
Lupus anticoagulant | 25 | 21.6 | 21 | 33.9 | 4 | 7.4 | f | .0006d* |
Anticardiolipin IgG antibody | 16 | 13.79 | 13 | 20.96 | 3 | 5.6 | f | .028d* |
Anticardiolipin IgM antibody | 14 | 12.1 | 10 | 16.13 | 4 | 7.4 | f | 0.16d |
Anti-β2 glycoprotein antibody | 6 | 5.17 | 4 | 6.45 | 2 | 3.7 | f | 0.68d |
Anti-Ro antibody | 3 | 2.6 | 3 | 4.83 | 0 | 0 | f | 0.24d |
Anti-La antibody | 2 | 1.72 | 2 | 3.23 | 0 | 0 | f | 0.49d |
Erythrocyte sedimentation rate | 33 (6–130) | 36 (6–99) | 25 (10–130) | u = 2.023 | 0.30b | |||
C-reactive protein | 3.2 (0.2–39) | 3.3 (0.3–39) | 3.2 (0.2–20.9) | U = 0.969 | 0.332b | |||
Serum albumin | 3.66 ± 0.59 | 3.52 ± 0.57 | 3.83 ± 0.49 | t = 3.13 | .002a* | |||
Alanine aminotransferase | 18 (6.7–46) | 19.2 (7.4–42) | 17 (6.7–46) | U = 2.079 | 0.41b | |||
Aspartate aminotransferase | 22 (9.1–48) | 21.5 (9.1–45) | 22 (12.3–48) | U = 2.742 | 0.32b | |||
Blood urea nitrogen | 2 2 (7–59) | 22 (7–59) | 23 (9–43) | U = 2.66 | 0.99b | |||
Creatinine | 0.5 (0.2–1.8) | 0.4 (0.3–1.8) | 0.5 (0.2–1.5) | U = 2.57 | 0.48b | |||
24-h urinary protein | 145.5 (70–6500) | 569 (78–6500) | 119.5 (70–932) | U = 6.128 | .000b* | |||
24-h urinary proteinuria > 500 mg, n (%) | 34 (29.3%) | 29 (46.8%) | 5 (9.3%) | 40.9 | 0.000c* | |||
Creatinine clearance | 94.2 (37–140) | 96 (3–140) | 91.2 (49.6–125) | U = 1.96 | 0.94b | |||