Hematological markers and ultrasound 7-joint inflammation score as add-on tools in the assessment of inflammation in rheumatoid arthritis patients

Gaballah, Abd Elatif Ahmed; Elsawy, Noha Abdelhalim; El Gendy, Wessam Mohamed; Afifi, Ahmed Hafez; Hanafi, Maha Saeid Mahmoud

doi:10.1186/s43166-022-00126-0

Egyptian Rheumatology and Rehabilitation

Table 3 Comparison between DAS 28 (CRP) categories regarding blood cell count and inflammatory markers

From: Hematological markers and ultrasound 7-joint inflammation score as add-on tools in the assessment of inflammation in rheumatoid arthritis patients

	DAS 28 (CRP)				P
	Remission (n = 9)	LDA (n = 8)	MDA (n = 22)	HAD (n = 15)	P
Hemoglobin (g/dl)
Min.–Max.	9.50–16.20	10.10–14.50	9.80–13.60	9.60–13.60	0.183
Mean ± SD.	12.84 ± 2.14	12.73 ± 1.48	12.02 ± 0.85	11.89 ± 1.01	0.183
RBCs (× 10⁶/μl)
Min.–Max.	3.81–5.84	3.89–5.91	3.61–5.21	3.74–5.21	0.407
Mean ± SD.	4.58 ± 0.67	4.78 ± 0.57	4.46 ± 0.49	4.46 ± 0.42	0.407
Platelets (× 10³/μl)
Min.–Max.	201.0–347.0	127.0–410.0	116.0–397.0	127.0–329.0	0.965
Mean ± SD.	253.9 ± 53.70	257.9 ± 101.5	245.1 ± 75.77	255.8 ± 67.10	0.965
WBCs (× 10³/μl)
Min.–Max.	4.0–8.38	3.48–8.93	4.25–14.30	3.48–7.83	0.856
Mean ± SD.	6.01 ± 1.42	6.42 ± 1.90	6.24 ± 2.42	5.80 ± 1.27	0.856
Neutrophils (× 10³/μl)
Min.–Max.	1.50–4.82	1.33–5.07	1.74–9.58	2.08–5.45	0.669
Median	3.03	2.96	3.12	3.77	0.669
Lymphocytes (x10³/ul)
Min.–Max.	1.46–2.72	0.96–3.40	0.87–4.05	0.80–2.40	0.022^*
Median	1.92	2.42	2.03	1.66	0.022^*
ESR (mm/h)
Min.–Max.	8.00–35.00	7.00–60.00	5.00–70.00	10.00–72.00	0.038*
Mean ± SD.	20.75 ± 10.00	18.96 ± 18.33	29.57 ± 17.73	37.33 ± 21.11	0.038*
CRP (mg/dl)
Min.–Max.	0.60–12.90	0.75–5.01	0.64–23.00	1.38–20.70	0.009*
Mean ± SD.	4.10 ± 3.90	2.91 ± 1.22	7.82 ± 6.63	9.91 ± 5.76	0.009*
PDW (fl)
Min.–Max.	11.60–14.30	10.50–15.10	10.90–16.70	11.00–14.90	0.536
Mean ± SD.	12.98 ± 1.12	12.28 ± 1.37	13.10 ± 2.00	13.14 ± 1.19	0.536
MPV (fl)
Min.–Max.	7.70–11.80	7.10–13.50	7.60–12.20	0.20–13.50	0.651
Median	10.0	10.15	10.10	9.80	0.651
RDW (%)
Min.–Max.	12.40–16.80	12.40–18.0	11.10–18.0	10.20–16.90	0.579
Median	13.35	13.50	14.0	14.10	0.579
NLR
Min.–Max.	0.59–2.66	0.58–2.72	0.75–4.02	1.45–4.95	0.018*
Median	1.55	1.32	1.66	2.19	0.018*
PLR
Min.–Max.	73.80–198.17	59.11–198.99	58.72–302.89	81.80–338.87	0.027*
Median	128.34	115.81	124.59	174.81	0.027*

P value ≤0.01: highly significant
DAS Disease activity score, LDA Low disease activity, MDA Moderate disease activity, HDA High disease activity, RBCs Red blood cells, WBCs White blood cells, ESR Erythrocyte sedimentation rate, CRP C reactive protein, PDW Platelet distribution width, MPV Mean platelet volume, RDW Red cell distribution width, NLR Neutrophil-lymphocyte ratio, PLR Platelet lymphocyte ratio
*Statistically significant at P≤ 0.05

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