Hematological markers and ultrasound 7-joint inflammation score as add-on tools in the assessment of inflammation in rheumatoid arthritis patients

Gaballah, Abd Elatif Ahmed; Elsawy, Noha Abdelhalim; El Gendy, Wessam Mohamed; Afifi, Ahmed Hafez; Hanafi, Maha Saeid Mahmoud

doi:10.1186/s43166-022-00126-0

Egyptian Rheumatology and Rehabilitation

Table 2 Comparison between DAS 28 ESR categories regarding blood cell count and inflammatory markers

From: Hematological markers and ultrasound 7-joint inflammation score as add-on tools in the assessment of inflammation in rheumatoid arthritis patients

	DAS 28 (ESR)				P
	Remission (n = 9)	LDA (N = 8)	MDA (N = 22)	HAD (N = 15)	P
Hemoglobin (g/dl)
Min.–Max.	9.50–16.20	10.10–14.40	9.80–14.20	9.60–13.30	0.167
Mean ± SD.	13.09 ± 2.09	12.31 ± 1.32	12.04 ± 1.02	11.98 ± 0.90	0.167
RBCs( ×10⁶/μl)
Min.–Max.	3.81–5.84	4.17–5.91	3.61–5.21	3.74–5.21	0.198
Mean ± SD.	4.54 ± 0.61	4.90 ± 0.58	4.47 ± 0.50	4.45 ± 0.40	0.198
Platelets (×10³/μl)
Min.–Max.	127.0–347.0	171.0–410.0	116.0–397.0	116.0–322.0	0.907
Mean ± SD.	244.4 ± 64.12	266.0 ± 99.47	254.8 ± 75.91	244.1 ± 68.69	0.907
WBCs (×10³/μl)
Min.–Max.	3.48–8.38	6.66–8.93	3.48–14.30	4.07–7.83	0.036*
Mean ± SD.	5.54 ± 1.50	7.86 ± 0.92	5.92 ± 2.36	5.82 ± 1.16	0.036*
Neutrophils (×10³/μl)
Min.–Max.	1.50–4.82	2.63–5.10	1.33–9.58	2.18–5.45	0.051
Median	2.19	4.16	3.0	3.17	0.051
Lymphocytes (×10³/μl)
Min.–Max.	0.96–2.72	1.73–3.40	0.87–4.05	0.80–2.40	0.016*
Median	1.93	2.74	1.87	1.72	0.016*
ESR (mm/h)
Min.–Max.	8.0–30.0	5.0–35.0	10.0–60.0	10.0–72.0	<0.001*
Mean ± SD.	16.56 ± 8.78	11.20 ± 9.75	28.32 ± 13.96	45.0 ± 20.17	<0.001*
CRP (mg/dl)
Min.–Max.	0.60–6.40	1.20–12.90	0.64–23.0	0.64–20.70	0.031*
Mean ± SD.	3.10 ± 1.67	4.08 ± 3.75	7.82 ± 6.53	9.47 ± 6.04	0.031*
PDW (fl)
Min.–Max.	11.60–14.30	11.50–15.10	10.50–16.70	11.0–14.90	0.749
Mean ± SD.	12.72 ± 0.97	13.21 ± 1.45	12.74 ± 2.01	13.23 ± 1.21	0.749
MPV (fl)
Min.–Max.	7.70–13.50	7.10–10.80	8.50–13.50	0.20–11.80
Median	10.30	8.80	10.45	9.80
RDW (%)
Min.–Max.	12.40–16.80	12.50–18.0	11.10–18.0	10.20–16.90
Median	13.10	14.70	13.75	14.10
NLR
Min.–Max.	0.59–2.49	1.02–2.66	0.58–4.95	1.30–3.70
Median	1.32	1.65	1.68	1.86
PLR
Min.–Max.	73.80–198.2	59.11–145.9	58.72–338.8	72.70–338.9	0.134
Median	132.2	117.7	134.2	170.3	0.134

DAS Disease activity score, LDA Low disease activity, MDA Moderate disease activity, HDA High disease activity, RBCs Red blood cells, WBCs White blood cells, ESR Erythrocyte sedimentation rate, CRP C reactive protein, PDW Platelet distribution width, MPV Mean platelet volume, RDW Red cell distribution width, NLR Neutrophil-lymphocyte ratio, PLR Platelet-lymphocyte ratio
*Statistically significant at P≤ 0.05, P value ≤0.01: highly significant

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