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Table 1 Key questions used to develop the guidelines

From: Egyptian consensus on treat-to-target approach of gout: evidence-based clinical practice guidelines for the management of gout

Domains

Key questions

Targeted patients:

Who are the targeted patients?

Treatment target:

What is the treatment target?

Treatment of gout flare:

What is the best strategy for treatment of gout flare?

What is the recommended duration of treatment of gout flare?

Treatment of recurrent gout

What is the approach for treatment of recurrent gout?

What is the advised timing of starting ULT therapy?

When to consider switching ULT treatment?

What is the management approach in case of failure to achieve targeted serum urate despite ULT dose escalation?

Prophylaxis against gout flare

What is the best approach for prophylaxis against gout flare?

Management of refractory gout

What is the best management approach for refractory gout?

Long-term management of gout

What is the strategy for long-term management of gout?

Patient’s education and lifestyle advice:

What are the main points to be included in the patients’ education program for gout patients?

Comorbidities screening

Should people with gout be screened for comorbidities?

Management of gout in patients with CKD and patients on dialysis

What is the best approach for management of gout in patients with CKD?

Is there specific management strategy for people with gout on dialysis?

Recommendations for specific medications and pregnancy:

Are there specific recommendations for specific medications used commonly for patients with gout?