Table 2 Comparisons of the allele and genotype frequency distribution of the ESR-α (rs 2234693) in SLE patients and the control subjects
ESR-α rs 2234693 | SLE patients (n = 30) (%) | Control subjects (n = 20) (%) | OR | 95% CI | P value |
|---|---|---|---|---|---|
T allele | 20 (33.3%) | 27 (67.5%) | 1 | Reference | |
C allele | 40 (66.7%) | 13 (32.5%) | 4.1 | 1.7-9.7 | 0.001* |
TT | 3 (10) | 10 (50%) | 1 | Reference | |
TC | 14 (46.7%) | 7 (35%) | 6.6 | 1.3-32.2 | 0.01* |
CC | 13 (43.3%) | 3 (15%) | 14.4 | 2.3-87.4 | 0.003* |