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Table 3 Association between ADAMTS14 gene rs4747096 single nucleotide polymorphism genotype and different clinical and radiological features of the hand joints in the generalized osteoarthritis patient group

From: Association between primary osteoarthritis and ADAMTS14 single nucleotide polymorphism in Egyptian population: a case-control study

Different clinical and radiological features of the hand joints

ADAMTS14 gene rs4747096 SNP genotype

Test of significanceb

P

AA (n = 10)

AG (n = 13)

Number of affected hand joints

 Min.-Max.

21.00–22.00

6.00–22.00

16.500

0.002*

 Median

22.00

15.00

  

Number of deformed hand joints

 Min.-Max.

0.00–10.00

0.00–.00

64.000

0.976

 Median

1.50

1.00

  

Number of joints with Heberden node

 Min.-Max.

0.00–8.00

0.00–4.00

59.000

0.738

 Median

2.50

2.00

  

Number of joints with Bouchard node

 Min.-Max.

4.00–8.00

1.00–8.00

48.000

0.313

 Median

8.00

6.00

  

PIP KL

 Grade Ia

0 (0.0)

4 (30.8)

  

 Grade IIa

0 (0.0)

6 (46.2)

(χ2) 13.618

0.003*

 Grade IIIa

7 (70.0)

2 (15.4)

  

 Grade IVa

3 (30.0)

1 (7.7)

  

Thumb IP KL

 Normala

0 (0.0)

1 (7.7)

  

 Grade Ia

0 (0.0)

5 (38.5)

(χ2) 10.676

0.030*

 Grade IIa

5 (50.0)

2 (15.4)

  

 Grade IIIa

4 (40.0)

1 (7.7)

  

 Grade IVa

1 (10.0)

4 (30.8)

  
  1. ADAMTS a disintegrin and metalloproteinase with thrombospondin motifs, IP interphalangeal joint, KL Kellgren-Lawrence scale, Max. maximal, Min. minimal, n number of patients, P P value for comparing between AA and AG, PIP proximal interphalangeal joint, SNP single nucleotide polymorphism, χ2 value of the chi-square test
  2. *Statistically significant at P ≤ 0.05
  3. aData are presented as number and percentage
  4. bValue of the Mann-Whitney test