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Egyptian Rheumatology and Rehabilitation

Table 6 Agreement (sensitivity, specificity) for baseline of adenosine 2A receptor relative quantification and adenosine 3 receptor relative quantification to discriminate between non-responder (n = 8) and responder cases (n = 57)

From: The implication of adenosine receptor expression in prediction of methotrexate clinical response in Egyptian rheumatoid arthritis patients

Baseline of

AUC

P

95% CI

Cut-off#

Sensitivity

Specificity

PPV

NPV

ADORA2a RQ

0.961

< 0.001*

0.913–1.008

≤ 1.4

75.0

91.23

54.5

96.3

ADORA3 RQ

0.964

< 0.001*

0.917–1.010

≤ 1.6

62.50

96.49

71.4s

94.8

  1. AUC area under a curve, P value probability value, CI confidence intervals,
  2. NPV negative predictive value, PPV positive predictive value
  3. *Statistically significant at P ≤ 0.05
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