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Table 6 Comparison between the different types of MEFV gene mutation according to different Musculoskeletal manifestations

From: Musculoskeletal and neurological manifestations in a cohort of Egyptian Familial Mediterranean fever patients: genotype-phenotype correlation

 

Total (n=135)

M694V (n=39)

V726A (n=20)

M6801 (n=37)

E148Q (n=25)

M694I (n=14)

p

No. (%)

No. (%)

No. (%)

No. (%)

No. (%)

No. (%)

Arthralgia

Low back pain

24 (17.8%)

9 (23.1%)

4 (21.1%)

5 (13.9%)

4 (16.7%)

2 (15.4%)

MCp=0.850

Knee

34 (25.2%)

6 (15.4%)

6 (31.6%)

13 (36.1%)

6 (25%)

3 (23.1%)

MCp=0.367

Feet

25 (18.5%)

9 (23.1%)

4 (21.1%)

6 (16.7%)

4 (16.7%)

2 (15.4%)

MCp=0.939

Ankle

32 (23.7%)

10 (25.6%)

4 (20%)

8 (21.6%)

6 (24%)

4 (28.6%)

MCp=0.088

Wrist and hand

12 (8.9%)

2 (5.1%)

3 (15.8%)

2 (5.6%)

3 (12.5%)

2 (15.4%)

MCp=0.476

Arthritis

55 (40.7%)

16 (41%)

5 (25%)

21 (56.8%)

8 (32%)

5 (35.7%)

MCp=0.140

Myalgia

28 (19.3%)

8 (20.5%)

5 (25%)

7 (18.9%)

5 (20%)

3 (21.4%)

MCp=0.247

  1. MC Monte Carlo