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Table 5 Comparison between the different types of MEFV gene mutation according to Colchicine dose and ESR level

From: Musculoskeletal and neurological manifestations in a cohort of Egyptian Familial Mediterranean fever patients: genotype-phenotype correlation

 

Total (n=135)

M694V (n=39)

V726A (n=20)

M6801 (n=37)

E148Q (n=25)

M694I (n=14)

p

No. (%)

No. (%)

No. (%)

No. (%)

No. (%)

No. (%)

Colchicine dose at diagnosis

1.5:3mg

110 (81.5%)

31 (79.5%)

17 (85%)

31 (83.8%)

18 (72%)

13 (92.9%)

MCp=0.607

Colchicine dose now

1.5:3 mg

117 (86.7%)

34 (87.2%)

17 (85%)

32 (86.5%)

21 (84%)

13 (92.9%)

MCp=0.970

ESR

10 – 20

12 (8.9%)

2 (5.1%)

2 (10%)

5 (13.5%)

2 (8%)

1 (7.1%)

MCp=0.804

20 – 50

77 (57%)

20 (51.3%)

10 (50%)

21 (56.8%)

15 (60%)

11 (78.6%)

MCp=0.450

50 – 100

43 (31.9%)

15 (38.5%)

8 (40%)

11 (29.7%)

7 (28%)

2 (14.3%)

MCp=0.458

  1. χ2: Chi square test MC: Monte Carlo
  2. p p value for comparing between the different types of genetic mutation
  3. *: Statistically significant at p ≤ 0 05