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Table 2 Baseline demographic, comorbidities, and associated diseases in two groups of COVID patients

From: Anti-phospholipid antibodies in the setting of thromboembolic events associated with severe COVID-19 pneumonia

Demographic variable

Patients with thrombotic events (n = 65)

Patients without thrombotic events (n = 108)

P value

Demographics

Age (years)

57.46(12.03)

50.87(14.76)

0.002*1

Gender

 Male

 Female

49(75.4)

16(24.6)

71(65.7)

37(34.3)

0.1832

Nationality

 Saudi

 Non-Saudi

26(40)

39(60)

48(44.4)

60(55.6)

0.5672

BMI (kg/m2)

27.36((23.5–31.2)

26.02(24.04–31.23)

0.9443

Smoking

 No smoking

23(35.4)

64(59.3)

 

 Smoker

 Unknown

39(60.0)

3(4.6)

29(26.9)

15(13.9)

< 0.001*2

Comorbidities no. (%)

 Diabetes mellitus

33(50.8)

43(39.8)

0.1602

 Hypertension

29(44.6)

38(35.2)

0.2182

 Ischemic heart disease

16(24.6)

17(15.7)

0.1502

 Heart failure

6(9.2)

6(5.6)

0.3702

 Renal failure

4(6.2)

7(6.5)

1.0002

 Malignancy

1(1.5)

0

NA

 Sickle cell disease

0

3(2.8)

NA

 HIV

0

1(0.9)

NA

Pulmonary disease (other than pulmonary embolism) no. (%)

 No

62(95.4)

90(83.3)

 

 COPD

1(1.5)

7(6.5)

 

 Asthma

 Tuberculosis

 IPF

 Pulmonary HTN

1(1.5)

0

0

1(1.5)

8(7.4)

2(1.9)

1(0.9)

0

0.1102

Sign and symptoms (at presentation to hospital) no. (%)

 Fever

50(76.9)

80(74.1)

0.6752

 Cough

54(83.1)

85(78.7)

0.4832

 Sore throat

24(36.9)

47(43.5)

0.3932

 Dyspnea

58(89.2)

98(90.7)

0.7472

 Hemoptysis

7(10.8)

11(10.2)

0.9032

 Chest pain

25(38.5)

26(24.1)

0.044*2

 Vomiting

12(18.5)

28(25.9)

0.2592

 Diarrhea

16(24.6)

33(30.6)

0.4012

 Nausea

22(33.8)

39(36.1)

0.7632

 Loss of smell

6(9.2)

18(16.7)

0.1712

 Loss of taste

8(12.3)

17(15.7)

0.5342

 Headache

28(43.1)

42(38.9)

0.5872

 Bone ache

37(56.9)

64(59.3)

0.7632

 Limb weakness

4(6.15)

0

NA

 Calf pain

4(6.15)

0

NA

 Abdominal tenderness

2(3.08)

0

NA

 Other no. (%)

Duration of stay at hospital (days)

16(10–23)

14(10–20.75)

0.4683

Duration between admission and suspicion of thrombosis

7(3–10)

5(3–9.75)

0.5093

Outcomes (survival) no. (%)

 Survived

 Died

47(72.3)

18(27.7)

74(68.5)

34(31.5)

0.5992

 ICU admission (yes)

51(78.5)

80(74.1)

0.5152

 Intubation (yes)

39(60.0)

60(55.6)

0.5672

 Duration of stay at the  ICU

6(1–11)

5.5(0-13)

0.7583

  1. Values are the mean and SD, median (IQR) or n (%), BMI body mass index, kg/m2 mean (SD), HIV human immunodeficiency virus, COPD chronic obstructive pulmonary disease, IPF idiopathic pulmonary fibrosis, HTN hypertension. ICU intensive care unit, NA not applicable
  2. 1Independent-sample t test
  3. 2Chi-square test
  4. 3Mann-Whitney test