From: Implication of plasma gelsolin in systemic lupus erythematosus patients
Parameter | SLE patients (n = 50) |
---|---|
Age (years) | Mean ± SD 38.5 ± 6.3 Range (26–51) |
Disease duration (years) | Median (IQR) 5 (3–9.3) |
Clinical manifestations: | No. (%) |
Renal | 18 (36) |
Musculoskeletal | 17 (34) |
Skin | 50 (100) |
Cardiac | 11 (22) |
Chest | 12 (24) |
SLEDAI | Mean ± SD 13.1 ± 4.5 Range (4–22) |
Low | No. (%) 2 (4) |
Moderate | 16 (32) |
High | 25 (50) |
Very high | 7 (14) |
SDI | Median (IQR) 2 (1–3) |
Laboratory findings | Median (IQR) |
Hemoglobin (g/dl) | 10.6 (9.2–12.9) |
WBCs (× 103/ml) | 4.8 (3.7–8.4) |
Platelets (× 103/ml) | 231 (199.5–302.8) |
ESR (mm/h) | 60 (47–75) |
CRP (mg/dl) | 10.3 (6.3–13) |
Protein/24 h (mg/24 h) | 255 (107–679) |
Serum creatinine (mg/dl) | 0.97 (0.84–1.12) |
Blood urea (mg) | 22.8 (20–41.3) |
Protein/creatinine ratio | 0.23 (0.12–0.52) |
ANA positive | 50 (100) |
Anti-ds DNA positive | 23 (46) |
Plasma gelsolin (mg/l) | Median (IQR) 74.9 (57.5–98.8) |
Renal biopsy done for 18 | |
Class I | No. (%) 0 (0) |
Class II | 6 (12) |
Class III | 5 (10) |
Class IV | 7 (14) |