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Table 1 Characteristics and laboratory findings of the systemic lupus erythematosus (SLE) patients

From: Implication of plasma gelsolin in systemic lupus erythematosus patients

Parameter

SLE patients (n = 50)

Age (years)

Mean ± SD 38.5 ± 6.3 Range (26–51)

Disease duration (years)

Median (IQR) 5 (3–9.3)

Clinical manifestations:

No. (%)

 Renal

18 (36)

 Musculoskeletal

17 (34)

 Skin

50 (100)

 Cardiac

11 (22)

 Chest

12 (24)

SLEDAI

Mean ± SD 13.1 ± 4.5 Range (4–22)

 Low

No. (%) 2 (4)

 Moderate

16 (32)

 High

25 (50)

 Very high

7 (14)

SDI

Median (IQR) 2 (1–3)

Laboratory findings

Median (IQR)

 Hemoglobin (g/dl)

10.6 (9.2–12.9)

 WBCs (× 103/ml)

4.8 (3.7–8.4)

 Platelets (× 103/ml)

231 (199.5–302.8)

 ESR (mm/h)

60 (47–75)

 CRP (mg/dl)

10.3 (6.3–13)

 Protein/24 h (mg/24 h)

255 (107–679)

 Serum creatinine (mg/dl)

0.97 (0.84–1.12)

 Blood urea (mg)

22.8 (20–41.3)

 Protein/creatinine ratio

0.23 (0.12–0.52)

 ANA positive

50 (100)

 Anti-ds DNA positive

23 (46)

 Plasma gelsolin (mg/l)

Median (IQR) 74.9 (57.5–98.8)

Renal biopsy done for 18

 Class I

No. (%) 0 (0)

 Class II

6 (12)

 Class III

5 (10)

 Class IV

7 (14)

  1. Results are presented as mean ± SD (range) or median ± IQR or n (%)
  2. SLE systemic lupus erythematosus, SLEDAI SLE disease activity index, SDI SLE damage index, WBCs white blood cells, ESR erythrocyte sedimentation rate, CRP C-reactive protein, ANA anti-nuclear antibodies, anti-ds DNA anti-double-stranded deoxyribonucleic acid