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Table 5 Comparison of distribution of RF, anti-CCP, and PDUS grading among the VEGF gene SNP rs3025039 in RA patients

From: Effect of vascular endothelial growth factor gene polymorphisms on disease activity in rheumatoid arthritis

 

CC

CT

TT

Chi-square test

N

%

n

%

n

%

χ2

P

RF

 −ve

13

26.5

10

38.5

0

0.0

  

 +ve

36

73.5

16

61.5

5

100.0

3.332

0.189

Anti-CCP titer (n, %)

 −ve

18

36.7

11

42.3

3

60.0

  

 +ve

31

63.3

15

57.7

2

40.0

1.109

0.574

PDUS findings (n, %)

 Grade 1

15

30.6

3

11.5

0

0.0

  

 Grade 2

34

69.4

17

65.4

1

20.0

  

 Grade 3

0

0.0

6

23.1

4

80.0

32.327

< 0.001

  1. Level of significance at P ≤ 0.05
  2. VEGF vascular endothelial growth factor, anti-CCP anti-cyclic citrullinated peptide, PDUS power Doppler ultrasound, RF rheumatoid factor