Table 4 Comparison of the clinical features, activity indices, and laboratory findings among the VEGF gene SNP rs3025039 in RA patients
CC | CT | TT | ANOVA test | ||
|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Mean ± SD | F | P | |
Clinical findings | |||||
Duration of RA (years) | 8.1 ± 3.3 | 8.4 ± 3.0 | 8.8 ± 4.4 | 0.130 | 0.878 |
Duration of morning stiffness (minutes) | 131.6 ± 62.3 | 146.5 ± 64.5 | 168.0 ± 80.4 | 0.998 | 0.373 |
TJC | 10.9 ± 2.1 | 11.8 ± 2.1 | 13.6 ± 2.9 | 4.125 | 0.020 |
SJC | 9.6 ± 1.7 | 10.4 ± 2.0 | 12.4 ± 3.0 | 5.719 | 0.005 |
VAS pain (mm) | 51.7 ± 11.5 | 56.7 ± 9.2 | 58.0 ± 2.0 | 2.357 | 0.102 |
Composite activity indices | |||||
DAS-28 ESR | 3.6 ± 1.3 | 4.2 ± 1.4 | 5.4 ± 0.9 | 6.215 | 0.003 |
Laboratory findings | |||||
ESR (mm/hour) | 46.5 ± 15.3 | 56.2 ± 20.0 | 75.0 ± 20.6 | 7.619 | < 0.001 |
CRP (mg/dl) | 25.7 ± 10.5 | 28.3 ± 13.3 | 35.5 ± 8.8 | 1.867 | 0.162 |