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Egyptian Rheumatology and Rehabilitation

Table 3 Comparison of alleles and genotyping distribution of VEGF gene SNP rs3025039 between RA patients and controls

From: Effect of vascular endothelial growth factor gene polymorphisms on disease activity in rheumatoid arthritis

 

RA patients

Controls

Chi-square test

  

N

%

n

%

χ2

P

OR,

95% CI

HWE

    

2.413

0.112

  

Alleles

 C allele

124

77.5

144

90.0

    

 T allele

36

22.5

16

10.0

9.185

0.002

1.559

1.23–1.97

Genotyping

 CC

49

61.2

66

82.5

    

 CT

26

32.5

12

15.0

    

 TT

5

6.3

2

2.5

8.957

0.011

  
  1. Level of significance at P ≤ 0.05
  2. HWE Hardy-Weinberg equilibrium, CI confidence interval, OR odds ratio, VEGF vascular endothelial growth factor
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