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Table 3 Association between serum calprotectin and response to biologic therapy

From: Could potentially calprotectin be a promising biomarker to oracle biologic therapy response in rheumatoid arthritis?

 

Non-responders (n = 6)

Moderate responders (n = 18)

Good responder (n = 1)

Test of significance

Serum calprotectin before treatment (ng/ml)

Median (range)

388.35 (60.0–486.0)

415.65 (130.8–908.2)

488.7 (488.7–488.7)

P = 0.526*

Serum calprotectin after treatment (ng/ml)

Median (range)

96.18 (39.9–919.05)

136.80 (45.45–390.20)

140.55 (140.55–140.55)

P= 0.746*

 

z = 0.734

P= 0.463

z = 3.72

P <0.001**

NA

(Only one case)

 

% of reduction

37.5%

68.7%

71.2%

 
  1. Abbreviations: NA not applicable, n number
  2. **P ≤ 0.05; statistically significant
  3. *Calculated using Kruskal–Wallis test