Egyptian Rheumatology and Rehabilitation

Table 1 Comparison of allele distribution of TLR9 gene SNP rs187084 and TLR5 gene SNP rs5744168 between SLE patients and controls

From: Toll-like receptor 5 and Toll-like receptor 9 single nucleotide polymorphisms and risk of systemic lupus erythematosus and nephritis in Egyptian patients

	SLE patients		Controls		Chi-square test		OR [95% CI]
	n	%	n	%	X²	P	OR [95% CI]
TLR5-rs5744168 SNP
C allele [R]	387	96.8	393	98.3
T allele	13	3.3	7	1.8	1.846	0.174	1.89 [0.75–4.78]
TLR9-rs187084 SNP
C allele [R]	167	41.8	179	44.8
T allele	233	58.3	221	55.3	0.733	0.392	1.130 [0.85–1.49]
TLR9-rs352140 SNP
C allele	223	55.8	195	48.8
T allele [R]	177	44.3	205	51.3	3.928	0.047*	1.32 [1.00–1.75]

The chi-square test is used. P is set significant if ≤ 0.05, significant values are marked by *
TLR Toll-like receptor, SNP Single nucleotide polymorphism, SLE Systemic lupus erythematosus, OR Odds ratio, CI Confidence interval, R Reference allele

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