Table 3 Comparison of total WOMAC score between neural prolotherapy and intra-articular prolotherapy

 At baseline

63.8 ± 8.2

61.2 ± 7.3

1.522

0.132

 Immediate

36.8 ± 10.3

55.5 ± 8.0

9.158

< 0.001

 At 3 months

37.5 ± 10.6

57.2 ± 8.8

9.199

< 0.001

 At 6 months

39.8 ± 10.5

58.5 ± 8.3

8.919

< 0.001

 F

69.787

3.262

 P

< 0.001

0.023

 At baseline

14.5 ± 2.0

14.6 ± 1.7

0.181

0.857

 Immediate

6.5 ± 1.3

12.6 ± 2.3

14.984

< 0.001

 At 3 months

6.9 ± 1.5

13.2 ± 2.3

15.001

< 0.001

 At 6 months

7.6 ± 1.7

13.7 ± 2.2

13.715

< 0.001

 F

218.784

6.066

 P

< 0.001

< 0.001

 At baseline

4.1 ± 1.2

4.2 ± 1.1

0.197

0.845

 Immediate

1.6 ± 0.8

3.1 ± 1.1

6.951

< 0.001

 At 3 months

1.8 ± 1.0

3.5 ± 1.2

7.004

< 0.001

 At 6 months

2.7 ± 1.1

3.7 ± 1.1

4.211

< 0.001

 F

49.956

6.948

 P

< 0.001

< 0.001

 At baseline

43.0 ± 5.9

42.4 ± 4.9

1.341

0.184

 Immediate

28.7 ± 8.6

39.8 ± 5.4

7.027

< 0.001

 At 3 month

28.8 ± 8.8

40.4 ± 5.8

7.065

< 0.001

 At 6 months

29.6 ± 8.9

41.0 ± 5.4

6.988

< 0.001

 F

34.638

1.510

 P

< 0.001

0.214