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Table 2 Laboratory results of poly JIA and SOJIA

From: Tocilizumab in management of refractory juvenile idiopathic arthritis, 10 years of experience at tertiary university hospital

Parameter

Poly JIA

Mean (± SD)

SOJIA

Mean (± SD)

Reference range

P value

CBC

 Hemoglobin, gm/dl

11.3 (1.9)

9.3 (1.07)

9.6–15.6

0.042

 WBCs, K/μL

10.3 (4.5)

18.7 (6.9)

5.5–17.5

0.042

 Platelets, K/μL

487.8 (196.3)

529 (171.6)

150–450

0.797

ESR, mm/h

45 (53.9)

65.7 (41.8)

0–10

0.364

CRP, mg/L

26.04 (40.6)

120.5 (59.8)

0–3

0.019

Liver enzymes

 AST, U/L

16 (2.4)

23.1 (11.7)

15–37

0.240

 ALT, U/L

24.2 (12.2)

31.1 (17.9)

12–78

0.364

Renal functions

 Urea, mmol/L

3.9 (1.1)

3.6 (1.4)

2.5–6.4

0.699

 Creatinine, μmol/L

42.4 (12.7)

32.1 (9.4)

53–115

0. 240

Ferritin, ng/ml

17 (13.8)

1814.4 (3417.9)

30–400

0.024

RF positive n. (%)

2 (14.3%)

0 (0.0)

< 20

0.110

A-CCP positive n. (%)

2 (14.3%)

0 (0.0)

< 20

0.110

ANA positive n. (%)

3 (21.4%)

4 (28.6%)

< 1:40

1

  1. Abbreviations: CBC complete blood count, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, AST aspartate transaminase, ALT alanine transaminase, RF rheumatoid factor, A-CCP anticyclic citrullinated peptide, ANA antinuclear antibody