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Table 6 Agreement (sensitivity, specificity) for PINP and B-ALP to discriminate osteoporosis patients (n = 60) from osteopenia patients (n = 48)

From: Could procollagen type I N-terminal propeptide (PINP) and bone alkaline phosphatase (B-ALP) be valid alternative diagnostic markers to dual X-ray absorptiometry (DEXA) in elderly females with osteoporosis? An Egyptian radiological and laboratory monocentric study

 

AUC

p

95% CI

Cut off

Sensitivity

Specificity

PPV

NPV

PINP (pg/ml)

0.721

< 0.001*

0.625–0.818

≤ 37.2

71.67

62.50

70.5

63.8

B-ALP (ng/ml)

0.584

0.137

0.475–0.692

> 51.2

58.33

56.25

62.5

51.9

  1. AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
  2. *Statistically significant at p ≤ 0.05