Egyptian Rheumatology and Rehabilitation

Table 5 Agreement (sensitivity, specificity) for PINP and B-ALP to discriminate osteoporosis patients (n = 60) from healthy control (n = 60)

From: Could procollagen type I N-terminal propeptide (PINP) and bone alkaline phosphatase (B-ALP) be valid alternative diagnostic markers to dual X-ray absorptiometry (DEXA) in elderly females with osteoporosis? An Egyptian radiological and laboratory monocentric study

	AUC	p	95% CI	Cutoff^#	Sensitivity	Specificity	PPV	NPV
PINP (pg/ml)	0.892	< 0.001^*	0.835–0.949	≤40.6^#	86.67	80.0	81.2	85.7
B-ALP (ng/ml)	0.925	< 0.001^*	0.881–0.969	> 40.3^#	85.0	83.33	83.6	84.7

AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
^*Statistically significant at p ≤ 0.05
^#Cutoff was choose according to the Youden index

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