Egyptian Rheumatology and Rehabilitation

Table 4 Agreement (sensitivity, specificity) for PINP and B-ALP to discriminate osteopenia patients (n = 48) from healthy control (n = 60)

From: Could procollagen type I N-terminal propeptide (PINP) and bone alkaline phosphatase (B-ALP) be valid alternative diagnostic markers to dual X-ray absorptiometry (DEXA) in elderly females with osteoporosis? An Egyptian radiological and laboratory monocentric study

	AUC	p	95% CI	Cut off^#	Sensitivity	Specificity	PPV	NPV
PINP (pg/ml)	0.775	< 0.001^*	0.689–0.861	≤ 44.7^#	75.0	66.67	64.3	76.9
B-ALP (ng/ml)	0.945	< 0.001^*	0.906–0.983	> 41.2^#	89.58	85.0	82.7	91.1

AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
^*Statistically significant at p ≤ 0.05
^#Cutoff was choose according to the Youden index

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