Skip to main content
Egyptian Rheumatology and Rehabilitation

Table 3 Comparison between the mean serum and synovial levels of IL-37 in the studied groups

From: Interleukin-37 as an anti-inflammatory cytokine: does its relation to disease activity suggest its potential role in rheumatoid arthritis therapy?

IL-37 (Mean ± SD)

Studied groups

P

RA patients

PKOA

Healthy control

Range (mean ± SD)

Serum IL-37 pg/ml

250–550

21–122

22–110

< 0.001*

P1 < 0.001*

P2 < 0.001*

P3 = 0.94

382.6±73.97

70.38±27.49

69.97±25.12

Synovial IL-37 pg/ml

450–780

23–142

–

< 0.001*

625.44±73.92

80.8±27.66

P

< 0.001*

0.06

  
  1. RA rheumatoid arthritis, PKOA primary knee osteoarthritis, IL-37 interleukin-37, SD standard deviation, pg/ml picogram per milliliter, P ≤ 0.05* significant difference, P > 0.05 non-significant, P1 difference between RA and POA patients regarding the mean serum IL-37 level, P2 difference between RA patients and healthy control groups regarding the mean serum IL-37 level, P3 difference between PKOA patients and healthy control groups regarding the mean serum IL-37 level
Back to article page