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Table 2 Relation between mortality and demographic, laboratory and immunological parameters

From: Mortality in a cohort of Egyptian systemic lupus erythematosus patients: retrospective two-center study

 

Mortality

P

Survived (n = 737)

Died (n = 34)

Personal history

 Sex

  Male

59 (8%)

4 (11.8%)

FEp = 0.351

  Female

678 (92%)

30 (88.2%)

 Age (years)

  Mean ± SD.

28.2 ± 8.7

28.4 ± 11.3

0.576

  Median (min.–max.)

27 (12–60)

27 (12–67)

 Age of onset

  Mean ± SD.

22.1 ± 8.6

23.1 ± 9.4

0.647

  Median (min.–max.)

20 (2–52)

20 (10–49)

 Duration (years)

  Mean ± SD.

6.1 ± 4.7

5.7 ± 5.4

0.223

  Median (min.–max.)

5 (0.2–34)

4 (0.3–22)

Lab

 Anemia

584 (79.2%)

33 (97.1%)

0.011*

 Autoimmune

136 (18.5%)

9 (26.5%)

0.242

 Leucopenia

  Mean ± SD.

0.6 ± 0.8

0.7 ± 0.8

0.264

  Median (min.–max.)

0 (0–3.9)

1 (0–3)

 Lymphopenia

287 (38.9%)

26 (76.5%)

< 0.001*

 Neutropenia

67 (9.1%)

8 (23.5%)

FEp = 0.012*

 Leucocytosis

156 (21.2%)

17 (50%)

< 0.001*

 Thrombocytopenia

151 (20.5%)

18 (52.9%)

< 0.001*

 Thrombocytosis

102 (13.8%)

9 (26.5%)

FEp = 0.075

Autoimmune profile

 ANA

696 (94.4%)

31 (91.2%)

FEp = 0.435

 Anti-DNA

483 (65.5%)

19 (55.9%)

0.248

 Decreased C3

434 (58.9%)

29 (85.3%)

0.002*

 Decreased C4

359 (48.7%)

22 (64.7%)

0.068

 Anti Smith

50 (6.8%)

2 (5.9%)

FEp = 1.000

  1. Anti-dsDNA Anti-double stranded DNA antibodies, ANA Antinuclear antibody, C3 Complement 3, C4 Complement 4, χ2 Chi-square test, FE Fisher exact, U Mann-Whitney test, P p value for association between different categories
  2. *Statistically significant at p ≤ 0.05