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Table 3 Comparison of socio-demographic characteristics, clinical findings, and radiological findings between male knee osteoarthritis patients in low serum uric acid group versus high serum uric acid group

From: Association of serum uric acid with clinical and radiological severity of knee osteoarthritis in non-gouty patients

 

L-sUA group

H-sUA group

p

Age (years) (mean ± SD)

60.3 ± 6.5

59.6 ± 7.1

0.703*

Residence

 Rural

17, 54.8%

10, 50.0%

 

 Urban

14, 45.2%

10, 50.0%

0.735**

Educational level (n, %)

 Basic

8, 25.8%

6, 30.0%

 

 Secondary

9, 29.0%

5, 25.0%

 

 Higher

14, 45.2%

9, 45.0%

0.928**

BMI (kg/m2) (mean ± SD)

22.7 ± 1.6

23.0 ± 1.6

0.512*

Duration of KOA (years)

10.1 ± 3.5

9.9 ± 3.7

0.787*

WOMAC score (mean ± SD)

 Pain subscale

8.1 ± 3.9

9.4 ± 4.0

0.242*

 Stiffness subscale

2.3 ± 1.2

2.5 ± 1.1

0.542*

 Function subscale

30.8 ± 9.8

32.8 ± 10.5

0.512*

 Total score

41.2 ± 14.2

44.7 ± 14.4

0.403*

KL grade (n, %)

 Grade 2

10, 32.3%

4, 20.0%

 

 Grade 3

12, 38.7%

7, 35.0%

 

 Grade 4

9, 29.0%

9, 45.0%

0.452**

Osteophytes (n, %)

 Grade 2

15, 48.4%

5, 25.0%

 

 Grade 3

8, 25.8%

7, 35.0%

 

 Grade 4

8, 25.8%

8, 40.0%

0.243**

JSW (mm) (median [IQR])

1.10 [0.80]

1.05 [1.73]

0.575***

Focal erosion (n, %)

14, 45.2%

13, 65.0%

0.166**

Bone marrow lesions (n, %)

11, 35.5%

9, 45.0%

0.497**

Effusion (n, %)

20, 64.5%

10, 50.0%

0.304**

Synovitis (n, %)

7, 22.6%

8, 40.0%

0.183**

Soft tissue swelling (n, %)

12, 38.7%

9, 45.0%

0.656**

  1. KOA knee OA, L-sUA low serum uric acid, H-sUA high serum uric acid, SD standard deviation, BMI body mass index, WOMAC Western Ontario and McMaster Universities OA Index, KL Kellgren-Lawrence, JSW joint space width, mm millimeters, IQR interquartile range
  2. * Student’s t test, ** chi-square test, *** Mann-Whitney U test, significance level was set at p ≤ 0.05