Egyptian Rheumatology and Rehabilitation

Table 2 Comparison of socio-demographic characteristics, clinical findings, and radiological findings between female knee osteoarthritis patients in low serum uric acid group versus high serum uric acid group

From: Association of serum uric acid with clinical and radiological severity of knee osteoarthritis in non-gouty patients

	L-sUA group	H-sUA group	P
Age (years) (mean ± SD)	59.4 ± 5.6	59.5 ± 6.7	0.970*
Residence (n, %)
Rural	37, 41.6%	10, 43.5%
Urban	52, 58.4%	13, 56.5%	0.869**
Educational level (n, %)
Basic	28, 31.5%	5, 21.7%
Secondary	25, 28.1%	6, 26.1%
Higher	36, 40.4%	12, 52.2%	0.549**
BMI (kg/m²) (mean ± SD)	22.6 ± 1.4	22.7 ± 1.7	0.790*
Duration of KOA (years) (mean ± SD)	10.9 ± 3.1	10.7 ± 3.7	0.732*
WOMAC score (mean ± SD)
Pain subscale	8.4 ± 3.5	10.9 ± 4.0	0.003*
Stiffness subscale	2.1 ± 1.0	2.7 ± 1.3	0.015*
Function subscale	30.7 ± 9.8	36.9 ± 9.6	0.008*
Total score	41.2 ± 13.6	50.5 ± 13.6	0.004*
KL grade (n, %)
Grade 2	48, 53.9%	6, 26.1%
Grade 3	31, 34.8%	8, 34.8%
Grade 4	10, 11.2%	9, 39.1%	0.003**
Osteophytes (n, %)
Grade 2	45, 50.6%	3, 13.0%
Grade 3	35, 39.3%	7, 30.4%
Grade 4	9, 10.1%	13, 56.5%	<0.001**
JSW (mm) (median [IQR])	2.40 [1.60]	1.30 [2.10]	0.016***
Focal erosion (n, %)	33, 37.1%	17, 73.9%	0.002**
Bone marrow lesions (n, %)	27, 30.3%	13, 56.5%	0.019**
Effusion (n, %)	28, 31.5%	8, 34.8%	0.761**
Synovitis (n, %)	36, 40.4%	17, 73.9%	0.004**
Soft tissue swelling (n, %)	28, 31.5%	9, 39.1%	0.486**

KOA knee OA, L-sUA low serum uric acid, H-sUA high serum uric acid, SD standard deviation, BMI body mass index, WOMAC Western Ontario and McMaster Universities OA Index, KL Kellgren-Lawrence, JSW joint space width, mm millimeters, IQR interquartile range
* Student’s t test, ** chi-square test, *** Mann-Whitney U test, significance level was set at p ≤ 0.05

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