Egyptian Rheumatology and Rehabilitation

Table 1 Comparison of socio-demographic characteristics, clinical findings, and radiological findings between knee osteoarthritis patients in low serum uric acid group versus high serum uric acid group

From: Association of serum uric acid with clinical and radiological severity of knee osteoarthritis in non-gouty patients

	L-sUA group	H-sUA group	P
Age (years) (mean ± SD)	59.7 ± 5.8	59.5 ± 6.8	0.898*
Females sex (, %)	89, 74.2%	23, 53.5%	0.012**
Residence (n, %)
Rural	54, 45.0%	20, 46.5%
Urban	66, 55.0%	23, 53.5%	0.864**
Educational level (n, %)
Basic	36, 30.0%	11, 25.6%
Secondary	34, 28.3%	11, 25.6%
Higher	50, 41.7%	21, 48.8%	0.714**
BMI (kg/m²) (mean ± SD)	22.6 ± 1.4	22.8 ± 1.6	0.452*
Duration of KOA (years) (mean ± SD)	10.7 ± 3.2	10.3 ± 3.7	0.469*
WOMAC score (mean ± SD)
Pain subscale	8.3 ± 3.6	10.2 ± 4.0	0.004*
Stiffness subscale	2.2 ± 1.1	2.6 ± 1.2	0.019*
Function subscale	30.8 ± 9.8	35.0 ± 10.1	0.018*
Total score	41.2 ± 13.7	47.8 ± 14.1	0.008*
KL grade (n, %)
Grade 2	58, 48.3%	10, 23.3%
Grade 3	43, 35.8%	15, 34.9%
Grade 4	19, 15.8%	18, 41.9%	< 0.001**
Osteophytes (n, %)
Grade 2	60, 50.0%	8, 18.6%
Grade 3	43, 35.8%	14, 32.6%
Grade 4	17, 14.2%	21, 48.8%	< 0.001**
JSW (mm) (median [IQR])	1.75 [1.67]	1.10 [1.70]	0.013***
Focal erosion (n, %)	47, 39.2%	30, 69.8%	< 0.001**
Bone marrow lesions (n, %)	38, 31.7%	22, 51.2%	0.023**
Effusion (n, %)	48, 40.0%	18, 41.9%	0.831**
Synovitis (n, %)	43, 35.8%	25, 58.1%	0.011**
Soft tissue swelling (n, %)	40, 33.3%	18, 41.9%	0.316*

KOA knee OA, L-sUA low serum uric acid, H-sUA high serum uric acid, SD standard deviation, BMI body mass index, WOMAC Western Ontario and McMaster Universities OA Index, KL Kellgren-Lawrence, JSW joint space width, mm millimeters, IQR interquartile range
* Student’s t test, ** chi-square test, *** Mann-Whitney U test, significance level was set at p ≤ 0.05

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