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Egyptian Rheumatology and Rehabilitation

Table 3 Comparison between the two studied groups regarding MISS score

From: Does caffeine reduce methotrexate intolerance in patients with rheumatoid arthritis: a randomized controlled study

MISS score

Group A (n = 60)

Group B (n = 30)

P

Time 0 (baseline)

Mean ± SD

8.1 ± 1.5

7.6 ± 1.3

0.202

Range

6–12

6–10

Time 1 (after 1 month)

Mean ± SD

3.5 ± 7.9

7.9 ± 1.3

0.001*

Range

0–9

6–11

Time 2 (after 2 months)

Mean ± SD

2.6 ± 2.5

8.2 ± 1.5

0.001*

Range

0–9

6–12

Time3 (after 3 months)

Mean ± SD

1.7 ± 2.3

8.2 ± 1.5

0.001*

Range

0–9

6–12

P0

0.001*

0.017*

 

P1

0.001*

0.053

 

P2

0.001*

0.033*

 

P3

0.001*

0.033*

 
  1. P P value for independent student t test for comparison between the two studied groups, P0 P value for repeated measures ANOVA test for comparison in between the same group, P1 P value for Bonferroni post hoc test between time 0 and time 1 in the same group, P2 P value for Bonferroni post hoc test between time 0 and time 2 in the same group, P3 P value for Bonferroni post hoc test between time 0 and time 3 in the same group
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